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Ghrelin, Growth Hormone and Growth Factors at High Altitude

This study has been completed.
Information provided by:
Medical University of Vienna Identifier:
First received: August 24, 2009
Last updated: February 22, 2010
Last verified: August 2009

Regulation of ghrelin, growth hormone and growth factors at high altitude and their change during ascent to high altitude has not been studied in depth yet. The study includes 33 volunteers (12f) investigated at sea level, 4 days after ascent to 3440m and 14 days after ascent to 5400-5900m.

The investigators hypothesized that during ascent growth hormone levels would increase to compensate for the higher energy needs at high altitude.

Condition Intervention
Healthy Growth Hormone Other: exposure to high altitude

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by Medical University of Vienna:

Primary Outcome Measures:
  • Ghrelin, growth hormone, insulin-like growth factor I (IGF-I), IGF binding protein 1 (IGFBP1), IGF binding protein 2 (IGFBP2), IGF binding protein 3 (IGFBP3), acid-labile subunit (ALS), insulin, prolactin [ Time Frame: 14 days ]

Study Start Date: April 2002
Study Completion Date: September 2005
Groups/Cohorts Assigned Interventions
probands Other: exposure to high altitude


Ages Eligible for Study:   18 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Healthy Caucasians from an Alpinist association

Inclusion Criteria:

  • Healthy and good physical fitness
  Contacts and Locations
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No Contacts or Locations Provided
  More Information

Responsible Party: Prof Herwig Frisch, Pediatric Department Identifier: NCT00966134     History of Changes
Other Study ID Numbers: EK 411
Study First Received: August 24, 2009
Last Updated: February 22, 2010

Keywords provided by Medical University of Vienna:
mountain medicine
growth hormone
physiology of hormonal adaptation to high altitude processed this record on August 23, 2017