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Ghrelin, Growth Hormone and Growth Factors at High Altitude

This study has been completed.
ClinicalTrials.gov Identifier:
First Posted: August 26, 2009
Last Update Posted: February 23, 2010
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Medical University of Vienna

Regulation of ghrelin, growth hormone and growth factors at high altitude and their change during ascent to high altitude has not been studied in depth yet. The study includes 33 volunteers (12f) investigated at sea level, 4 days after ascent to 3440m and 14 days after ascent to 5400-5900m.

The investigators hypothesized that during ascent growth hormone levels would increase to compensate for the higher energy needs at high altitude.

Condition Intervention
Healthy Growth Hormone Other: exposure to high altitude

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by Medical University of Vienna:

Primary Outcome Measures:
  • Ghrelin, growth hormone, insulin-like growth factor I (IGF-I), IGF binding protein 1 (IGFBP1), IGF binding protein 2 (IGFBP2), IGF binding protein 3 (IGFBP3), acid-labile subunit (ALS), insulin, prolactin [ Time Frame: 14 days ]

Study Start Date: April 2002
Study Completion Date: September 2005
Groups/Cohorts Assigned Interventions
probands Other: exposure to high altitude


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Healthy Caucasians from an Alpinist association

Inclusion Criteria:

  • Healthy and good physical fitness
  Contacts and Locations
No Contacts or Locations Provided
  More Information

Responsible Party: Prof Herwig Frisch, Pediatric Department
ClinicalTrials.gov Identifier: NCT00966134     History of Changes
Other Study ID Numbers: EK 411
First Submitted: August 24, 2009
First Posted: August 26, 2009
Last Update Posted: February 23, 2010
Last Verified: August 2009

Keywords provided by Medical University of Vienna:
mountain medicine
growth hormone
physiology of hormonal adaptation to high altitude