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Treatment of Male Pattern Baldness With Botulinum Toxin

This study has been completed.
Information provided by:
The Crown Institute Identifier:
First received: August 24, 2009
Last updated: NA
Last verified: August 2009
History: No changes posted
This proof of concept study seeks to demonstrate that Botulinum toxin injections are a safe and effective method for treating this form of hair loss.

Condition Intervention Phase
Male Pattern Baldness Drug: Botulinum Toxin - A injections Phase 2

Study Type: Interventional
Study Design: Primary Purpose: Screening
Official Title: A Prospective, Single Center, Open Label, Proof of Principle Study to Assess the Efficacy and Safety of 150 Units of Botulinum Toxin-A Intra-Muscular Injection in the Prevention of Hair Loss in Men With Androgenetic Alopecia

Resource links provided by NLM:

Further study details as provided by The Crown Institute:

Primary Outcome Measures:
  • Hair Growth [ Time Frame: 1 year ]

Secondary Outcome Measures:
  • Hair Loss [ Time Frame: 1 year ]

Study Start Date: December 2002
Study Completion Date: June 2004
Primary Completion Date: June 2004 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years to 65 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Male pattern baldness
  • Norwood II-VI

Exclusion Criteria:

  • Treatment with Botulinum toxins or other hair growth interventions with past year
  Contacts and Locations
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Please refer to this study by its identifier: NCT00965640

Canada, Ontario
Crown Institute
Pickering, Ontario, Canada, L1V 1B1
Sponsors and Collaborators
The Crown Institute
Principal Investigator: Brian Freund, MD Crown Institute
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Dr. B. Freund, Principal Investigator, Crown Institute Identifier: NCT00965640     History of Changes
Other Study ID Numbers: MPB-2002-01
HPB 081023
Study First Received: August 24, 2009
Last Updated: August 24, 2009

Keywords provided by The Crown Institute:
male pattern baldness
androgenetic alopecia
hair loss

Additional relevant MeSH terms:
Alopecia Areata
Hair Diseases
Skin Diseases
Pathological Conditions, Anatomical
Botulinum Toxins
Acetylcholine Release Inhibitors
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Cholinergic Agents
Neurotransmitter Agents
Physiological Effects of Drugs processed this record on September 21, 2017