The Effects of Kuvan on Functional Brain Connectivity in Individuals With Phenylketonuria (PKU)
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|ClinicalTrials.gov Identifier: NCT00964236|
Recruitment Status : Completed
First Posted : August 24, 2009
Last Update Posted : January 4, 2018
|Condition or disease||Intervention/treatment|
|Study Type :||Observational|
|Actual Enrollment :||20 participants|
|Official Title:||The Effects of Kuvan on Functional Brain Connectivity in Individuals With Phenylketonuria (PKU)|
|Study Start Date :||August 2009|
|Primary Completion Date :||August 2010|
|Study Completion Date :||August 2011|
Individuals with phenylketonuria (PKU) who are beginning treatment with Kuvan (sapropterin).
Sapropterin (Kuvan) 20mg/kg/day taken once daily or as otherwise prescribed by physician as standard care.
Other Name: Kuvan
Healthy individuals without phenylketonuria (PKU).
- functional magnetic resonance imaging of the brain [ Time Frame: baseline, 4 week, & 6 month follow-up ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00964236
|United States, Missouri|
|University of Missouri|
|Columbia, Missouri, United States, 65211|
|Principal Investigator:||Shawn E Christ, Ph.D.||University of Missouri-Columbia|