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Pediatric Bipolar Disorder Study at UCLA

This study has been completed.
Sponsor:
Collaborators:
National Institute of Mental Health (NIMH)
The State Family Fund
Information provided by (Responsible Party):
James McCracken, University of California, Los Angeles
ClinicalTrials.gov Identifier:
NCT00961935
First received: August 18, 2009
Last updated: January 12, 2016
Last verified: January 2016
  Purpose
The UCLA Semel Institute for Neuroscience in Los Angeles, CA, is conducting a study looking at similarities and differences in how the brain works between bipolar disorder and attention deficit hyperactivity disorder (ADHD).

Condition
Bipolar Disorder

Study Type: Observational
Study Design: Time Perspective: Cross-Sectional
Official Title: Examining Neurocognitive Profiles of Bipolar Disorder and Attention-Deficit Hyperactivity Disorder

Resource links provided by NLM:


Further study details as provided by University of California, Los Angeles:

Enrollment: 50
Study Start Date: August 2008
Study Completion Date: September 2011
Primary Completion Date: August 2011 (Final data collection date for primary outcome measure)
Detailed Description:
Children between the ages of 7 and 17 years old, with a diagnosis of Bipolar I, Bipolar II, or Bipolar NOS, are currently being recruited for this study looking at similarities and differences in how the brain works between bipolar disorder and attention deficit hyperactivity disorder (ADHD). The study involves a comprehensive evaluation at intake, cognitive assessment, EEG, and functional MRI, done over the course of 2 or 3 visits. This study does not provide treatment. However, with participants' consent, the assessment information can be shared with the child's clinician or psychiatrist and a letter with the results from cognitive testing can be prepared, which can be useful in school planning. Referrals for treatment can also be provided.
  Eligibility

Ages Eligible for Study:   7 Years to 17 Years   (Child)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Bipolar Disorder
Criteria

Inclusion Criteria:

  • Subject suffers clinically impairing symptoms of mood lability.
  • Child has resided with primary caretaker for at least 6 months.
  • Caretaker speaks sufficient English to complete all study evaluations and measures.

Exclusion Criteria:

  • Lifetime history of mental retardation, autism, or primary diagnosis of psychosis.
  • Subject is pregnant or nursing.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00961935

Locations
United States, California
UCLA Semel Institute for Neuroscience and Human Behavior
Los Angeles, California, United States, 90095
Sponsors and Collaborators
University of California, Los Angeles
National Institute of Mental Health (NIMH)
The State Family Fund
Investigators
Principal Investigator: Patricia Walshaw, Ph.D. University of California, Los Angeles
  More Information

Publications:

Responsible Party: James McCracken, Chair, University of California, Los Angeles
ClinicalTrials.gov Identifier: NCT00961935     History of Changes
Other Study ID Numbers: P50MH077248-02  DNBBS B2-MBP 
Study First Received: August 18, 2009
Last Updated: January 12, 2016
Health Authority: United States: Federal Government

Keywords provided by University of California, Los Angeles:
bipolar disorder
child bipolar disorder
adolescent bipolar disorder
pediatric bipolar disorder
fMRI
MRI
EEG
neurocognitive tasks

Additional relevant MeSH terms:
Disease
Bipolar Disorder
Attention Deficit Disorder with Hyperactivity
Pathologic Processes
Bipolar and Related Disorders
Mental Disorders
Attention Deficit and Disruptive Behavior Disorders
Neurodevelopmental Disorders

ClinicalTrials.gov processed this record on December 08, 2016