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Effects of Ketamine on Human Bladders and Its Possible Mechanisms

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00957333
First Posted: August 12, 2009
Last Update Posted: January 14, 2016
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Taipei Medical University WanFang Hospital
  Purpose
This study is aimed to evaluate the relationship between ketamine abused and bladder dysfunction and its possible mechanisms.

Condition Intervention
Cystitis Other: ketamine

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Cross-Sectional
Official Title: Effects of Ketamine on Human Bladders and Its Possible Mechanisms

Resource links provided by NLM:


Further study details as provided by Taipei Medical University WanFang Hospital:

Primary Outcome Measures:
  • Substance Abuse Situation Record [ Time Frame: 1 day ]
    Substance abuse situation record: ketamine


Secondary Outcome Measures:
  • Urinary Bladder Capacity [ Time Frame: 1 day ]

Biospecimen Retention:   Samples Without DNA
1.Urine 2.Blood 3.Biopsy

Enrollment: 44
Study Start Date: March 2009
Study Completion Date: December 2011
Primary Completion Date: December 2009 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
case
ketamine + Cystitis
Other: ketamine
N.A.

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
primary care clinic
Criteria

Inclusion Criteria:

  • Adult male or female
  • Cystitis (the clinicians ruled out the causes of bacterial infection)
  • Frequent micturition
  • The clinicians are willing to sign the ICF

Exclusion Criteria:

  • Suffers from the urinary system disease, is not suitable to carry on the urinary bladder biopsy sampling
  • Suffers from other diseases, doctor recognized that is not suitable to carry on the sampling
  • The clinicians are not willing to sign the ICF
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00957333


Locations
Taiwan
Taipei Medical University-Wan Fang Hospital
Taipei, Taiwan
Sponsors and Collaborators
Taipei Medical University WanFang Hospital
Investigators
Principal Investigator: Ruei-Ming Chen, PhD Taipei Medical University-Wan Fang Hospital
  More Information

Responsible Party: Taipei Medical University WanFang Hospital
ClinicalTrials.gov Identifier: NCT00957333     History of Changes
Other Study ID Numbers: DOH98-NNB-1049
First Submitted: August 3, 2009
First Posted: August 12, 2009
Results First Submitted: December 8, 2015
Results First Posted: January 14, 2016
Last Update Posted: January 14, 2016
Last Verified: November 2010

Keywords provided by Taipei Medical University WanFang Hospital:
ketamine
bladder dysfunction
bladder mucosa
mechanisms

Additional relevant MeSH terms:
Cystitis
Urinary Bladder Diseases
Urologic Diseases
Ketamine
Analgesics
Sensory System Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Anesthetics, Dissociative
Anesthetics, Intravenous
Anesthetics, General
Anesthetics
Central Nervous System Depressants
Excitatory Amino Acid Antagonists
Excitatory Amino Acid Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action