Periodontal Treatment Associated With Hyperbaric Oxygen Therapy
|ClinicalTrials.gov Identifier: NCT00955643|
Recruitment Status : Completed
First Posted : August 10, 2009
Last Update Posted : August 10, 2009
|Condition or disease||Intervention/treatment||Phase|
|Periodontal Disease||Other: oxygen Other: other||Not Applicable|
Materials and Methods: In 20 patients diagnosed with severe generalized chronic periodontitis (pockets>7mm) with bleeding on probing, SRP was rendered in all pockets. Additionally, five consecutive hyperbaric sessions were administered in 10 patients after random allocation (SRP+HBOT). Clinical parameters were assessed at baseline up to 6 months: plaque index (PI), bleeding on probing, probing depth, clinical attachment level and BANA test.
Results: SRP+HBOT resulted in greater probing reduction and attachment gain than SRP alone 3 months after treatment (p<0.001). The BANA test was negative after 1 week only for sites in the SRP+HBOT group (p<0.05). However SRP+HBOT failed to show a significant difference from SRP group after 3 months were all BANA sites became negative (p>0.05).
Conclusion: These preliminary data suggest that hyperbaric oxygen therapy had a short-term beneficial effect on pocket reduction and bacterial elimination, and may be considered a potential therapy option to improve the clinical outcomes of scaling in severe cases of chronic periodontitis.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||20 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Single (Outcomes Assessor)|
|Official Title:||Periodontal Therapy in Severe Cases of Periodontitis: Preliminary Findings of Non-surgical Instrumentation With or Without Hyperbaric Oxygen Therapy (HBOT)|
|Study Start Date :||March 2002|
|Actual Study Completion Date :||April 2003|
Experimental: hyperbaric therapy
Hyperbaric therapy by oxygen
Experimental: dental scaling and root planing
dental scaling and cleaning
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00955643
|EBMSP Central Clinic|
|Salvador, Bahia, Brazil, 40000|