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Plasma Pharmacokinetics of Alkylresorcinol Metabolites; New Candidate Biomarkers for Whole Grain Rye and Wheat Intake (Rye-kinetics)

This study has been completed.
Samfundet Folkhälsan
Sigrid Jusélius Foundation
Information provided by:
Helsinki University Identifier:
First received: August 5, 2009
Last updated: NA
Last verified: August 2009
History: No changes posted
The purpose of this study is to investigate the kinetics of two known alkylresorcinol metabolites in human subjects after intake of high-fiber rye bread. Whole grain rye is the most abundant source of alkylresorcinols.

Kinetics of Alkylresorcinol Metabolites

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Kinetic Study of Two Known Alkylresorcinol Metabolites in Human Subjects After the Intake of Rye Fiber, the Most Abundant Source of Alkylresorcinols in Diet.

Further study details as provided by Helsinki University:

Enrollment: 15
Study Start Date: March 2009
Study Completion Date: May 2009
Primary Completion Date: April 2009 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   20 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
healthy, free-living females and males

Inclusion Criteria:

  • Healthy, volunteer

Exclusion Criteria:

  • Hemoglobin below 125 mmol/L in females and below 135 mmol/L in males use of antibiotics within 3 months before entering the study
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Please refer to this study by its identifier: NCT00953836

Folkhälsan Research Center
Helsinki, Finland, 00250
Sponsors and Collaborators
Helsinki University
Samfundet Folkhälsan
Sigrid Jusélius Foundation
Study Director: Matti J Tikkanen, M.D., prof. Department of Medicine, University of Helsinki, Helsinki, Finland
  More Information Identifier: NCT00953836     History of Changes
Other Study ID Numbers: 22/13/03/00/09
Study First Received: August 5, 2009
Last Updated: August 5, 2009

Keywords provided by Helsinki University:
alkylresorcinol metabolites
rye fiber processed this record on June 23, 2017