Plasma Pharmacokinetics of Alkylresorcinol Metabolites; New Candidate Biomarkers for Whole Grain Rye and Wheat Intake (Rye-kinetics)

This study has been completed.
Samfundet Folkhälsan
Sigrid Jusélius Foundation
Information provided by:
Helsinki University Identifier:
First received: August 5, 2009
Last updated: NA
Last verified: August 2009
History: No changes posted
The purpose of this study is to investigate the kinetics of two known alkylresorcinol metabolites in human subjects after intake of high-fiber rye bread. Whole grain rye is the most abundant source of alkylresorcinols.

Kinetics of Alkylresorcinol Metabolites

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Kinetic Study of Two Known Alkylresorcinol Metabolites in Human Subjects After the Intake of Rye Fiber, the Most Abundant Source of Alkylresorcinols in Diet.

Resource links provided by NLM:

Further study details as provided by Helsinki University:

Enrollment: 15
Study Start Date: March 2009
Study Completion Date: May 2009
Primary Completion Date: April 2009 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   20 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
healthy, free-living females and males

Inclusion Criteria:

  • Healthy, volunteer

Exclusion Criteria:

  • Hemoglobin below 125 mmol/L in females and below 135 mmol/L in males use of antibiotics within 3 months before entering the study
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Please refer to this study by its identifier: NCT00953836

Folkhälsan Research Center
Helsinki, Finland, 00250
Sponsors and Collaborators
Helsinki University
Samfundet Folkhälsan
Sigrid Jusélius Foundation
Study Director: Matti J Tikkanen, M.D., prof. Department of Medicine, University of Helsinki, Helsinki, Finland
  More Information

No publications provided Identifier: NCT00953836     History of Changes
Other Study ID Numbers: 22/13/03/00/09
Study First Received: August 5, 2009
Last Updated: August 5, 2009
Health Authority: Finland: Ethics Committee

Keywords provided by Helsinki University:
alkylresorcinol metabolites
rye fiber processed this record on November 25, 2015