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Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified June 2013 by Boner Attilio, Universita di Verona.
Recruitment status was:  Recruiting
Azienda Ospedaliera Universitaria Policlinico
Information provided by (Responsible Party):
Boner Attilio, Universita di Verona Identifier:
First received: August 3, 2009
Last updated: June 18, 2013
Last verified: June 2013

In this study will be consecutive enrolled children with asthma (classified according to GINA guidelines) and rhinitis (classified by ARIA guidelines); the investigators will research clinical personal and parental history regarding allergic diseases, exposition to passive smoking and interpretate hematochemical parameters markers of atopy. Skin Prick Tests will be performed. In this study the investigators will evaluate lung function parameters (spirometry with bronchial reversibility test and exercise induced bronchoconstriction, oscillometry, respiratory plethysmography, etc.), airway inflammatory indices such as exhaled nitric oxide at different flows, exhaled and nasal temperature, nasal cytology.

The aim of the study will be to evaluate possible correlation between these different parameters and clinical status of the patients.

Condition Intervention
Other: regular treatment

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Cross-Sectional
Official Title: Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis

Further study details as provided by Boner Attilio, Universita di Verona:

Primary Outcome Measures:
  • Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis [ Time Frame: Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis ]

Estimated Enrollment: 1000
Study Start Date: July 2009
Estimated Study Completion Date: December 2014
Estimated Primary Completion Date: December 2013 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
asthma and rhinitis control Other: regular treatment
regular treatment
Other Name: asthma treatment

Detailed Description:
Each patients will be evaluated by spirometry and then he will undergo exercise challenge in order to evaluate exercise-induced bronchoconstriction as a marker of asthma control. The test of the challenge will be correlate with childhood Asthma control test score,levels of control (GINA classification)and the different markers of airway inflammation and atopy.

Ages Eligible for Study:   5 Years and older   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
children with asthma and/or rhinitis visited at the outpatients clinic at the University of Verona will be invited to participate to the study

Inclusion Criteria:

  • patient with asthma and rhinitis

Exclusion Criteria:

  • age <5 years
  • chronic respiratory diseases
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00952835

Contact: Attilio Boner, MD --390458124615

Pediatric department University of Verona Recruiting
Verona, Italy, 37134
Contact: Attilio Boner, MD    --390458124615   
Principal Investigator: Attilio Boner, MD         
Sub-Investigator: Iolanda Chinellato, MD         
Sponsors and Collaborators
Universita di Verona
Azienda Ospedaliera Universitaria Policlinico
Principal Investigator: Attilio Boner, MD Universita di Verona
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Boner Attilio, full professor, Universita di Verona Identifier: NCT00952835     History of Changes
Other Study ID Numbers: AOV-1716
Study First Received: August 3, 2009
Last Updated: June 18, 2013

Keywords provided by Boner Attilio, Universita di Verona:
Exhaled Nitric oxide
lung function
vitamin d

Additional relevant MeSH terms:
Bronchial Diseases
Respiratory Tract Diseases
Lung Diseases, Obstructive
Lung Diseases
Respiratory Hypersensitivity
Hypersensitivity, Immediate
Immune System Diseases
Nose Diseases
Respiratory Tract Infections
Otorhinolaryngologic Diseases processed this record on May 25, 2017