The Validity of Forced Expiratory Maneuvers in Ataxia Telangiectasia Studied Longitudinally

The recruitment status of this study is unknown because the information has not been verified recently.
Verified August 2009 by Sheba Medical Center.
Recruitment status was  Active, not recruiting
Information provided by:
Sheba Medical Center Identifier:
First received: August 2, 2009
Last updated: August 3, 2009
Last verified: August 2009

Rationale: Forced spirometry maneuvers are not routinely performed in patients with Ataxia Telangiectasia (A-T), even though they suffer from respiratory illnesses.

Objectives: To study the feasibility and validity of forced spirometry in A-T patients.

Methods: Patients will perform spirometry during clinical visits. Parameters studied will be technical quality, relation to predicted values, age, pulmonary illness, body mass index, mutational status and mutation.

Ataxia Telangiectasia

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: The Validity of Forced Expiratory Maneuvers in Ataxia Teleangiectasia Studied Longitudinally

Resource links provided by NLM:

Further study details as provided by Sheba Medical Center:

Primary Outcome Measures:
  • spirometry measurements [ Time Frame: 3 years ] [ Designated as safety issue: No ]

Enrollment: 28
Study Start Date: July 2009
Estimated Study Completion Date: July 2009

Ages Eligible for Study:   3 Years to 20 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with Ataxia Telangiectasia who are followed and treated in the National A-T center at Safra Children's Hospital, Sheba Medical Center, Ramat-Gan, Israel

Inclusion Criteria:

  • Patients with proven Ataxia Telangiectasia

Exclusion Criteria:

  • inability to perform spirometry
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00951886

Pediatric Pulmonary Unit, The Edmond and Lily Safra Children's Hospital Chaim Sheba Medical Center, Tel HaShomer
Ramat-Gan, Israel, 52621
Sponsors and Collaborators
Sheba Medical Center
  More Information

Responsible Party: Sheba medical Center, Ori Efrati, MD, Principal Investigator, Sheba medical Center Identifier: NCT00951886     History of Changes
Other Study ID Numbers: SHEBA-08-5418-OE-CTIL 
Study First Received: August 2, 2009
Last Updated: August 3, 2009
Health Authority: Israel: Israeli Health Ministry Pharmaceutical Administration

Keywords provided by Sheba Medical Center:
Ataxia Teleangiectasia
Respiratory rare diseases

Additional relevant MeSH terms:
Ataxia Telangiectasia
Cerebellar Ataxia
Spinocerebellar Ataxias
Brain Diseases
Cardiovascular Diseases
Central Nervous System Diseases
Cerebellar Diseases
DNA Repair-Deficiency Disorders
Genetic Diseases, Inborn
Immune System Diseases
Immunologic Deficiency Syndromes
Metabolic Diseases
Nervous System Diseases
Neurocutaneous Syndromes
Neurologic Manifestations
Signs and Symptoms
Vascular Diseases processed this record on May 24, 2016