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The Validity of Forced Expiratory Maneuvers in Ataxia Telangiectasia Studied Longitudinally

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified August 2009 by Sheba Medical Center.
Recruitment status was:  Active, not recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT00951886
First Posted: August 4, 2009
Last Update Posted: August 4, 2009
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Sheba Medical Center
  Purpose

Rationale: Forced spirometry maneuvers are not routinely performed in patients with Ataxia Telangiectasia (A-T), even though they suffer from respiratory illnesses.

Objectives: To study the feasibility and validity of forced spirometry in A-T patients.

Methods: Patients will perform spirometry during clinical visits. Parameters studied will be technical quality, relation to predicted values, age, pulmonary illness, body mass index, mutational status and mutation.


Condition
Ataxia Telangiectasia

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: The Validity of Forced Expiratory Maneuvers in Ataxia Teleangiectasia Studied Longitudinally

Resource links provided by NLM:


Further study details as provided by Sheba Medical Center:

Primary Outcome Measures:
  • spirometry measurements [ Time Frame: 3 years ]

Enrollment: 28
Study Start Date: July 2009
Estimated Study Completion Date: July 2009
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   3 Years to 20 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with Ataxia Telangiectasia who are followed and treated in the National A-T center at Safra Children's Hospital, Sheba Medical Center, Ramat-Gan, Israel
Criteria

Inclusion Criteria:

  • Patients with proven Ataxia Telangiectasia

Exclusion Criteria:

  • inability to perform spirometry
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00951886


Locations
Israel
Pediatric Pulmonary Unit, The Edmond and Lily Safra Children's Hospital Chaim Sheba Medical Center, Tel HaShomer
Ramat-Gan, Israel, 52621
Sponsors and Collaborators
Sheba Medical Center
  More Information

Responsible Party: Sheba medical Center, Ori Efrati, MD, Principal Investigator, Sheba medical Center
ClinicalTrials.gov Identifier: NCT00951886     History of Changes
Other Study ID Numbers: SHEBA-08-5418-OE-CTIL
First Submitted: August 2, 2009
First Posted: August 4, 2009
Last Update Posted: August 4, 2009
Last Verified: August 2009

Keywords provided by Sheba Medical Center:
Ataxia Teleangiectasia
Spirometry
Respiratory rare diseases

Additional relevant MeSH terms:
Ataxia
Cerebellar Ataxia
Telangiectasis
Ataxia Telangiectasia
Dyskinesias
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms
Cerebellar Diseases
Brain Diseases
Central Nervous System Diseases
Vascular Diseases
Cardiovascular Diseases
Spinocerebellar Ataxias
Neurocutaneous Syndromes
Genetic Diseases, Inborn
DNA Repair-Deficiency Disorders
Metabolic Diseases
Immunologic Deficiency Syndromes
Immune System Diseases