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Cassia Cinnamon for Glucose Uptake in Young Women

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ClinicalTrials.gov Identifier: NCT00951639
Recruitment Status : Completed
First Posted : August 4, 2009
Last Update Posted : August 4, 2009
Sponsor:
Information provided by:

Study Description
Brief Summary:
The purpose of this study was to compare the acute effects of 5g of Cassia cinnamon, 50 minutes of endurance exercise performed at 70% of the heart rate reserve (correlated to VO2max), and 5g of cellulose placebo on blood glucose, serum insulin and insulin sensitivity following an oral glucose tolerance test 3 hours after administration of each intervention.

Condition or disease Intervention/treatment
Insulin Resistance Impaired Glucose Tolerance Prediabetes Dietary Supplement: Cassia cinnamon Procedure: 50 minutes exercise Dietary Supplement: Cellulose Powder

Study Design

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 10 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Supportive Care
Official Title: Cassia Cinnamon and Acute Endurance Exercise for the Enhancement of Glucose Uptake in Healthy Young Women
Study Start Date : February 2008
Primary Completion Date : May 2009
Study Completion Date : May 2009

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arms and Interventions

Arm Intervention/treatment
Experimental: 5g Cassia cinnamon
Experimental treatment group
Dietary Supplement: Cassia cinnamon
5g encapsulated ground bark administered once in experimental session
Other Name: Brand: Nature's Bounty
Active Comparator: 50 minutes endurnace exercise
Endurance exercise treatment known to influence blood glucose
Procedure: 50 minutes exercise
50 minutes treadmill endurance exercise at 70% of the heart rate reserve (correlated to VO2max)
Placebo Comparator: 5g Cellulose
Placebo equivalent in weight and appearance to experimental treatment
Dietary Supplement: Cellulose Powder
5g encapsulated powder administered during placebo experimental session


Outcome Measures

Primary Outcome Measures :
  1. Blood Glucose [ Time Frame: Baseline, 0, 30, 60, 90 and 120 minutes following OGTT ]

Secondary Outcome Measures :
  1. Serum Insulin [ Time Frame: Baseline, 0, 30, 60, 90 and 120 minutes following OGTT ]

Eligibility Criteria

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Ages Eligible for Study:   18 Years to 30 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Sedentary
  • BMI: 27-45
  • DXA body fat % greater than 30%
  • 18-30 years of age
  • Healthy
  • From the Baylor University campus and surrounding community
  • Regular sleep habits

Exclusion Criteria:

  • Not regular users of any species of cinnamon
  • Not diagnosed with any metabolic disorder or chronic medical condition
  • Not taking prescription medications for 2 months before the study
  • Not taking ergogenic aids for 2 months before the study
  • Not taking oral contraceptives for 2 months before the study
  • No IUD placed for 2 months before the study
Contacts and Locations

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To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00951639


Locations
United States, Texas
Baylor University Department of Health, Human Performance, and Recreation
Waco, Texas, United States, 76798
Sponsors and Collaborators
Baylor University
Investigators
Study Chair: Darryn S Willoughby, Ph.D. Baylor University
Principal Investigator: Jean L Gutierrez, Ph.D. Baylor University
More Information

Publications:
Responsible Party: Darryn Willoughby, Baylor University Department of Health, Human Performance, and Recreation
ClinicalTrials.gov Identifier: NCT00951639     History of Changes
Other Study ID Numbers: BaylorU_Cassia_Women
First Posted: August 4, 2009    Key Record Dates
Last Update Posted: August 4, 2009
Last Verified: August 2009

Keywords provided by Baylor University:
Cassia
Cinnamon
Blood Glucose
Endurance exercise
Acute exercise
Overweight
Obesity
Women

Additional relevant MeSH terms:
Insulin Resistance
Prediabetic State
Glucose Intolerance
Hyperinsulinism
Glucose Metabolism Disorders
Metabolic Diseases
Diabetes Mellitus
Endocrine System Diseases
Hyperglycemia