Study Comparing One Versus Two Cortisone Injections for Trigger Finger

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified February 2014 by Rothman Institute Orthopaedics.
Recruitment status was:  Recruiting
Information provided by:
Rothman Institute Orthopaedics Identifier:
First received: July 31, 2009
Last updated: February 10, 2014
Last verified: February 2014
Trigger finger, also known as stenosing tenosynovitis, is a painful condition that can cause discomfort and disability. Many physicians choose to locally inject cortisone into the infected finger although there is no current consensus as to how many injections are needed to achieve maximum relief. This study will be a prospective, randomized study to compare one versus two injections for the treatment of trigger finger.

Condition Intervention
Stenosing Tenosynovitis
Trigger Finger
Drug: One cortisone injection
Drug: Two cortisone Injections

Study Type: Interventional
Study Design: Intervention Model: Parallel Assignment
Primary Purpose: Treatment
Official Title: A Prospective, Randomized Study Comparing One vs. Two Cortisone Injections for Trigger Finger

Resource links provided by NLM:

Further study details as provided by Rothman Institute Orthopaedics:

Primary Outcome Measures:
  • To determine if there is a difference in the incidence of pain, stiffness, clicking or locking at 6 months following final injection

Secondary Outcome Measures:
  • To evaluate treatment response among diabetic patients
  • To evaluate treatment response between thumbs and fingers
  • To evaluate treatment response between nodular versus diffuse tenosynovitis

Estimated Enrollment: 392
Study Start Date: May 2009
Arms Assigned Interventions
Active Comparator: One injection Drug: One cortisone injection
Patients in this arm will receive one cortisone injection for the treatment of his/her symptoms
Active Comparator: Two Injections Drug: Two cortisone Injections
Subjects randomized to this treatment will receive two cortisone injections, 4-6 weeks apart


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Subject is greater than 18 years of age, presenting with stenosing tenosynovitis.
  • Subject is willing and able to provide informed consent.

Exclusion Criteria:

  • Patients who have previously undergone surgery for the treatment of trigger finger.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00951236

United States, New Jersey
Rothman Institute: Egg Harbor Township Location
Egg Harbor Township, New Jersey, United States, 08234
Rothman Institute: Manahawkin location
Manahawkin, New Jersey, United States, 08050
Rothman Institute: Vorhees location
Vorhees, New Jersey, United States, 08043
United States, Pennsylvania
Rothman Institute: Media location
Media, Pennsylvania, United States, 19063
Rothman Institute Center City Location
Philadelphia, Pennsylvania, United States, 19107
Rothman Institute, South Philadelphia Location
Philadelphia, Pennsylvania, United States, 19145
Rothman Institute, Northeast Philadelphia location
Philadelphia, Pennsylvania, United States, 19152
Sponsors and Collaborators
Rothman Institute Orthopaedics
Principal Investigator: Charles Leinberry, MD Rothman Institute
Principal Investigator: Pedro Beredjiklian, MD Rothman Institute
Principal Investigator: Emran Sheikh, MD Rothman Institute
  More Information

Responsible Party: Charles Leinberry, MD, Rothman Institute Identifier: NCT00951236     History of Changes
Other Study ID Numbers: RIUCLEI 09-01 
Study First Received: July 31, 2009
Last Updated: February 10, 2014

Keywords provided by Rothman Institute Orthopaedics:
Trigger Finger
Trigger Thumb

Additional relevant MeSH terms:
Trigger Finger Disorder
Tendon Entrapment
Muscular Diseases
Musculoskeletal Diseases
Cortisone acetate
Anti-Inflammatory Agents processed this record on January 19, 2017