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The Acute Effects of Coffee on Glucose Metabolism

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ClinicalTrials.gov Identifier: NCT00950898
Recruitment Status : Completed
First Posted : August 3, 2009
Last Update Posted : August 3, 2009
Sponsor:
Information provided by:
Brooklyn College of the City University of New York

Brief Summary:
The purpose of this study was to determine the acute effects of decaffeinated coffee, caffeinated coffee and caffeine on glucose metabolism in humans

Condition or disease Intervention/treatment
Type 2 Diabetes Other: decaff Other: caffcoff Other: caffeine Other: placebo

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 11 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single (Participant)
Primary Purpose: Basic Science
Official Title: Human Trial of the Acute Effects of Coffee on Glucose Metabolism
Study Start Date : November 2006
Primary Completion Date : June 2007
Study Completion Date : June 2007

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Caffeine
U.S. FDA Resources


Intervention Details:
    Other: decaff
    2 mugs of decaffeinated coffee
    Other: caffcoff
    2 mugs of caffeinated coffee
    Other: caffeine
    2 mugs of hot water containing caffeine
    Other: placebo
    2 mugs of hot water


Primary Outcome Measures :
  1. plasma glucose levels [ Time Frame: 0, 10, 30, 60, 90, and 120 minutes. ]

Secondary Outcome Measures :
  1. plasma insulin [ Time Frame: 0, 10, 30, 60, 90, and 120 minutes ]


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 35 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • healthy young males
  • nonsmokers
  • moderate alcohol users

Exclusion Criteria:

  • not on any medications that could alter glucose metabolism
  • no history of blood disorders

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00950898


Locations
United States, New York
Brooklyn College of the City University of New York
Brooklyn, New York, United States, 11210
Sponsors and Collaborators
Brooklyn College of the City University of New York
Investigators
Principal Investigator: James Greenberg, Ph.D. Brooklyn College of the City University of New York

Responsible Party: James Greenberg, PhD., Principal Investigator, Brooklyn College of the City University of New York
ClinicalTrials.gov Identifier: NCT00950898     History of Changes
Other Study ID Numbers: 07-020
First Posted: August 3, 2009    Key Record Dates
Last Update Posted: August 3, 2009
Last Verified: July 2009

Keywords provided by Brooklyn College of the City University of New York:
coffee
caffeine
glucose metabolism
insulin sensitivity
diabetes

Additional relevant MeSH terms:
Caffeine
Central Nervous System Stimulants
Physiological Effects of Drugs
Phosphodiesterase Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Purinergic P1 Receptor Antagonists
Purinergic Antagonists
Purinergic Agents
Neurotransmitter Agents