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Assessment of Response Rates and Yields for Two Tools for Early Detection of Non-diabetic Hyperglycaemia and Diabetes (ATTEND)

This study has been completed.
University Hospitals, Leicester
Information provided by (Responsible Party):
University of Leicester Identifier:
First received: July 30, 2009
Last updated: November 12, 2014
Last verified: July 2009
The purpose of this study is to establish the most effective method of increasing attendance to screening of type 2 Diabetes within a primary care setting within the backdrop of the NHS Health Check programme.

Condition Intervention
Other: Self Assessment
Other: Electronic risk score

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Screening
Official Title: Assessment of Response Rates and Yields for Two Tools for Early Detection of Non-diabetic Hyperglycaemia and Diabetes

Resource links provided by NLM:

Further study details as provided by University of Leicester:

Primary Outcome Measures:
  • Increase in response rates to invitation to 2nd stage blood test [ Time Frame: 12 months ]

Secondary Outcome Measures:
  • Increase in yield of OGTT positive results through filtering of high risk participants that pass 1st and 2nd stage screens [ Time Frame: 12 ]

Enrollment: 432
Study Start Date: April 2011
Study Completion Date: July 2014
Primary Completion Date: July 2014 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Self Assessment
Patients are approached and asked to complete a risk score that will determine their current risk of diabetes and the likelihood of requiring further testing.
Other: Self Assessment
Self assessment used to determine current risk of diabetes and likelihood of requiring further testing
Active Comparator: Electronic risk score
Patients diabetes riks is determined based on their data held on practice systems. Patients are then invited for further testing based on this score.
Other: Electronic risk score
Patients current risk of diabetes is determined by a electronic risk algorithm. They are then invited to attend fof further testing.

Detailed Description:
The University Hospitals of Leicester and The University of Leicester have developed a self-assessment risk score and a practice data risk score that can be used in a variety of setting to detect undiagnosed diabetes and impaired glucose regulation. This is done to establish a simple and effective 1st stage screen to identify those people at risk of diabetes and engage the public to increase the number of high risk individuals attending screening invitations but reducing the overall number of oral glucose tolerance tests. This study aims to test in a pragmatic way the use of such tools in a primary care setting administered by primary care staff as part of the NHS Health Check programme.

Ages Eligible for Study:   40 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • 40-75 years old (30 -75 years old if South Asian origin)

Exclusion Criteria:

  • Current diagnosis of diabetes
  • Terminal illness or mental incapacity
  Contacts and Locations
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Please refer to this study by its identifier: NCT00950313

United Kingdom
Leicester City PCT
Leicester, Leicestershire, United Kingdom
Sponsors and Collaborators
University of Leicester
University Hospitals, Leicester
Principal Investigator: Kamlesh Khunti, MD University of Leicester
  More Information

Responsible Party: University of Leicester Identifier: NCT00950313     History of Changes
Other Study ID Numbers: CLAHRC ED DIAB01
Study First Received: July 30, 2009
Last Updated: November 12, 2014

Keywords provided by University of Leicester:
Self assessment

Additional relevant MeSH terms:
Diabetes Mellitus
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases processed this record on May 24, 2017