Try our beta test site
IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more...

Effects of White Wine vs. Tea Intake During and an Alcoholic Digestive Following a High Fat, High Calorie Cheese Fondue Meal on Gastric Emptying and Abdominal Symptoms in Healthy Volunteers

This study has been completed.
Information provided by:
University of Zurich Identifier:
First received: July 20, 2009
Last updated: June 24, 2010
Last verified: June 2010

Tradition holds that the intake of different drinks with a meal has an important influence on the digestion of food and postprandial symptoms such as fullness, bloating and satiety; however this assumption have never been subjected to controlled study

A classic example is the Swiss cheese fondue. The intake of white wine, tea and cherry schnapps (Kirsch) are often attributed either positive or negative effects on the gastrointestinal tract.

In this study the effect of white wine vs. tea intake during and an alcoholic digestive following a high fat, high calorie Swiss fondue meal on gastric emptying and visceral perception will be investigated using a randomized, controlled study design.

The fondue will be labeled with non-radioactive 13C octanoate for assessment of gastric emptying by breath-test.

Condition Intervention Phase
Healthy Participants
Dietary Supplement: Ingestion of white wine vs. tea during and an alco
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Health Services Research

Resource links provided by NLM:

Further study details as provided by University of Zurich:

Primary Outcome Measures:
  • Effect of white wine vs. tea on gastric emptying [ Time Frame: 4 hours ]

Estimated Enrollment: 12
Study Start Date: August 2009
Study Completion Date: October 2009
Primary Completion Date: October 2009 (Final data collection date for primary outcome measure)
Intervention Details:
    Dietary Supplement: Ingestion of white wine vs. tea during and an alco
    4 x 50ml glasses of white wine (12% alcohol) or tea will be taken according to a randomization scheme After the meal 1 x 20ml of Kirsch (40% alcohol) or tea will be taken

Ages Eligible for Study:   19 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion criteria: • able to communicate well with the investigators and provide written consent

• Body Mass Index: 19-30 kg/m2

Exclusion criteria: • physical co-morbidity requiring active treatment

  • psychiatric (DSM IV) disorders limiting the ability to comply with study
  • use of medications influencing upper GI motility
  • evidence of current drug or alcohol abuse
  • history of gastrointestinal disease or surgery except appendicectomy or hernia repair
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00943696

Zurich, Switzerland
Sponsors and Collaborators
University of Zurich
Study Director: 01 Studienregister MasterAdmins UniversitaetsSpital Zuerich
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Dr. Mark Fox, University of Zurich Identifier: NCT00943696     History of Changes
Other Study ID Numbers: Fonduestudie_EKGs
Study First Received: July 20, 2009
Last Updated: June 24, 2010 processed this record on April 28, 2017