Effect of Epidural Steroid Injection on Bone Mineral Density in Postmenopausal Women
To evaluate for the effect of corticosteroid epidural injections on bone mineral density in postmenopausal women. Candidates for the study: Post menopausal women between the ages of 55 and 80. No history of bone disease. No thyroid/parathyroid disorder. not used injected or oral steroids in the last year. No recent smoking.
The purpose is to identify any significant change in bone mineral density with the use of epidural steroid injections. This may implicate the need for patient counseling regarding this possible side effect and the possible use of preventive measures to avoid this adverse effect.
|To Assess the Changes in Markers of Bone Turnover Over a Six Month Period After Epidural Steroid Inject To Assess the Changes in Bone Mineral Density.||Drug: Triamcinilone (kenalog)||Phase 4|
|Study Design:||Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Basic Science
|Official Title:||Effect of Epidural Steroid Injection on Bone Mineral Density In Postmenopausal Women|
- Measurements will be taken at baseline and then repeated at 3,6, and 12 months after treatment. [ Time Frame: 12 months ]
|Study Start Date:||July 2007|
|Study Completion Date:||July 2011|
|Primary Completion Date:||July 2011 (Final data collection date for primary outcome measure)|
Active Comparator: Epidural Steriod Injection
This study focuses on the changes in bone mineral density over time of the cohort previously described in the inclusion criteria (post-menopausal white women)
Drug: Triamcinilone (kenalog)
Epidural steroid injection of 80mg of Triamcinilone.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00941473
|United States, Michigan|
|Henry Ford Hospital W. Bloomfield|
|West Bloomfield, Michigan, United States, 48322|