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Metabolome and Microbiomic in Fecal Samples (MicroMet)

This study has been completed.
Information provided by:
Massachusetts General Hospital Identifier:
First received: July 9, 2009
Last updated: July 17, 2009
Last verified: July 2009
The purpose of this study is to evaluate the effects of storage and handling on fecal samples collected for metabolomic, proteomic and microbiomic and analysis.


Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Fecal Samples for Metabolomic and Microbiomic Studies: Effects of Preparation and Storage

Resource links provided by NLM:

Further study details as provided by Massachusetts General Hospital:

Primary Outcome Measures:
  • Microbiome and metabolome yield [ Time Frame: one month ]

Biospecimen Retention:   None Retained
Stool samples

Enrollment: 4
Study Start Date: April 2009
Study Completion Date: May 2009
Primary Completion Date: May 2009 (Final data collection date for primary outcome measure)
Microbiome, Metabolome, Stool, Toddler
healthy infant stool samples

Detailed Description:


Human fecal collection for clinical or research studies usually occurs at the residence of the subject, an environment not equipped with measures to accommodate proper preparation and storage of samples for microbiome and metabolome analysis.


To evaluate the effects of storage and handling on fecal samples collected for metabolomic, proteomic and microbiomic and analysis.


Fecal samples will be collected within several minutes of voiding from healthy infants at the time of diaper change at day-care center.

Samples will be divided into 7 tubes, and subjected to different storage temperatures, before preforming microbial analysis by DNA sequencing, and metabolome analysis by H1NMR spectroscoty.


Ages Eligible for Study:   12 Months to 20 Months   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Healthy toddlers in a day care center

Inclusion Criteria:

  • healthy
  • age 12-20 months
  Contacts and Locations
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Please refer to this study by its identifier: NCT00938028

United States, Massachusetts
MassGeneral for Children
Boston, Massachusetts, United States, 02114
Sponsors and Collaborators
Massachusetts General Hospital
Principal Investigator: Harland Winter, MD MGH
  More Information

Responsible Party: Harland Winter, MD, MassGeneral Hospital for Children Identifier: NCT00938028     History of Changes
Other Study ID Numbers: 2009p-000636
Study First Received: July 9, 2009
Last Updated: July 17, 2009

Keywords provided by Massachusetts General Hospital:
fecal samples
toddler processed this record on May 25, 2017