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Trial record 20 of 33551 for:    Placebo AND placebo effect

Placebo Effects on Blood Pressure Induced by Expectancy Manipulation

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00937196
Recruitment Status : Completed
First Posted : July 10, 2009
Last Update Posted : August 13, 2013
Information provided by (Responsible Party):
Karin Meissner, Ludwig-Maximilians - University of Munich

Brief Summary:
The objective of the present study was to examine the effects of a single placebo intervention on blood pressure and to investigate autonomic and psychological mediating mechanisms.

Condition or disease Intervention/treatment Phase
Blood Pressure Drug: Placebo globuli Drug: Histaminum hydrochloricum globuli Not Applicable

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 45 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Basic Science
Official Title: Effects of Placebos and Verbal Suggestions on Blood Pressure - Randomized Controlled Trial
Study Start Date : August 2006
Actual Primary Completion Date : March 2007
Actual Study Completion Date : March 2007

Arm Intervention/treatment
Active Comparator: Histaminum hydrochloricum globuli
To allow double-blind administration of the placebo pills going along with verbal suggestions of a blood-pressure-lowering effect
Drug: Histaminum hydrochloricum globuli
Experimental: Placebo globuli Drug: Placebo globuli
placebo globuli administered together with verbal suggestions of a hypotensive drug effect

No Intervention: No treatment

Primary Outcome Measures :
  1. Blood pressure (systolic, diastolic) [ Time Frame: minutes 1 to 30 after intervention ]

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 35 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • informed consent

Exclusion Criteria:

  • not meeting inclusion criteria
  • hypotension or hypertension
  • treated or untreated hypertension or hypotension
  • Severe systemic disorders (tumors, tbc, diabetes, asthma etc)
  • diseases that influence the cardiovascular or gastrointestinal system
  • intake of drugs affecting blood pressure and/or autonomic nervous system
  • pregnancy and lactation phase
  • body mass index >= 32
  • cardiovascular risk factors (diabetes, smoking)
  • drug or alcohol abuse
  • insufficient compliance
  • participation in another trial within the last three months

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00937196

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Institute of Medical Psychology, Ludwig-Maximilians-University Munich
Munich, Germany, 80336
Sponsors and Collaborators
Ludwig-Maximilians - University of Munich
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Principal Investigator: Karin Meissner, MD Ludwig-Maximilians - University of Munich

Additional Information:
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Responsible Party: Karin Meissner, PD Dr. med., Ludwig-Maximilians - University of Munich Identifier: NCT00937196     History of Changes
Other Study ID Numbers: KM-DZ-06
First Posted: July 10, 2009    Key Record Dates
Last Update Posted: August 13, 2013
Last Verified: August 2013