Effects of Cardiac Rehabilitation for Individuals With Transient Ischemic Attack
Recruitment status was Recruiting
It is hypothesized that the addition of formal cardiac rehabilitation to standard care will result in long-term improvements in cardiovascular fitness and functional capacity in individuals who have suffered a transient ischemic attack (TIA) or minor stroke.
Furthermore, it is proposed that the addition of cardiac rehabilitation will influence stroke risk, physical activity participation, strength, and quality of life.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Effects of Cardiac Rehabilitation for Individuals With Transient Ischemic Attack|
- Primary outcomes include improvements in cardiovascular fitness, functional capacity, and physical activity levels in individuals with TIA. This will be measured using a cardiopulmonary exercise test and a 6 minute walk test. [ Time Frame: Baseline, 6 months, 12 months ] [ Designated as safety issue: No ]
- Secondary outcome measures are plasma lipid analysis, questionnaires pertaining to quality of life, physical activity and diet diaries, and results from the Montreal Cognitive Assessment and MRI analysis. [ Time Frame: Baseline, 6 months, 12 months ] [ Designated as safety issue: No ]
|Study Start Date:||March 2010|
|Estimated Study Completion Date:||March 2013|
|Estimated Primary Completion Date:||March 2013 (Final data collection date for primary outcome measure)|
Participants in this group will participate in Cardiac Rehabilitation, carrying out an exercise program which will last 12 months and combine both resistance and aerobic training.
Behavioral: Cardiac Rehabilitation
Individualized cardiac rehabilitation for 12 months, including health education sessions, as well as supervised exercise classes which include aerobic and resistance training.
A transient ischemic attack (TIA) is defined as an episode of neurological dysfunction caused by focal brain ischemia lasting less than 24 hours. Once an individual has suffered a TIA, preventative measures can be taken to target modifiable risk factors, one of which is physical inactivity. The current proposal focuses on the use of an established model of care (cardiac rehabilitation (CR)) and applies it to those who have suffered a TIA in order to maximize physical activity and minimize risk of future cardiovascular events. This will be a one-group pre/post design study. Participants will undergo measures at baseline, 6 and 12 months (cardiovascular fitness, 6 minute walk test, quality of life, diet, strength, physical activity, and Framingham Profile stroke risk (plasma lipids, blood pressure, medication use)).
Please refer to this study by its ClinicalTrials.gov identifier: NCT00929994
|Contact: Dina Brooks, PhD||416-978-1739||Dina.Brooks@utoronto.ca|
|Toronto Rehabilitation Institute - Rumsey Center||Recruiting|
|Toronto, Ontario, Canada, M4G 1R7|
|Principal Investigator: Paul Oh, MD|
|Principal Investigator:||Dina Brooks, PhD||Toronto Rehabilitation Institute|
|Principal Investigator:||William E McIllroy, PhD||University of Waterloo|
|Principal Investigator:||Paul Oh, MD||Toronto Rehabilitation Institute|
|Principal Investigator:||Sandra Black, MD||Sunnybrook and Women's College Health Centre|