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Oxidative Stress Markers in Open and Laparoscopic Colectomy for Cancer

This study has been completed.
University of Ioannina
Information provided by:
G. Hatzikosta General Hospital Identifier:
First received: June 25, 2009
Last updated: NA
Last verified: June 2009
History: No changes posted
Contribution to the study of oxidative stress markers in laparoscopic vs open colectomy for colorectal cancer

Condition Intervention Phase
Colorectal Cancer Procedure: Open colectomy Procedure: laparoscopic colectomy Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Outcomes Assessor)
Official Title: Study of the Oxidative Stress in Patients With Colorectal Cancer. Open vs Laparoscopic Approach

Resource links provided by NLM:

Further study details as provided by G. Hatzikosta General Hospital:

Primary Outcome Measures:
  • Oxidative stress markers in patients with colorectal cancer operated with open or laparoscopic approach [ Time Frame: preoperative, intraoperative, 6h postop, 24h postop ]

Enrollment: 40
Study Start Date: January 2008
Primary Completion Date: June 2009 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Open group
Group of patients operated with open approach for colorectal cancer
Procedure: Open colectomy
Open colectomy. Epidural anaesthesia used
Active Comparator: laparoscopic group
Group of patients operated with laparoscopic approach for colorectal cancer
Procedure: laparoscopic colectomy
Laparoscopic colectomy. Epidural anaesthesia used


Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • colorectal cancer

Exclusion Criteria:

  • metastases
  • recurrent disease
  • chronic diseases
  Contacts and Locations
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Please refer to this study by its identifier: NCT00928928

G Hatzikosta General Hospital
Ioannina, Greece, 45001
Sponsors and Collaborators
G. Hatzikosta General Hospital
University of Ioannina
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: George Pappas-Gogos,MD, G Hatzikosta General Hospital, Ioannina, Greece Identifier: NCT00928928     History of Changes
Other Study ID Numbers: GH-1948-03
Study First Received: June 25, 2009
Last Updated: June 25, 2009

Keywords provided by G. Hatzikosta General Hospital:
Lipid peroxidation
Protein peroxidation
DNA peroxidation
RNA peroxidation
Oxidative stress markers
Open surgery
Laparoscopic surgery

Additional relevant MeSH terms:
Colorectal Neoplasms
Intestinal Neoplasms
Gastrointestinal Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Digestive System Diseases
Gastrointestinal Diseases
Colonic Diseases
Intestinal Diseases
Rectal Diseases processed this record on September 21, 2017