Try our beta test site
IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more...

Tooth Mousse and Fluoride in Dentin Hypersensitivity Treatment

This study has been completed.
National Natural Science Foundation of China
Information provided by:
Huazhong University of Science and Technology Identifier:
First received: June 22, 2009
Last updated: NA
Last verified: June 2009
History: No changes posted
GC Tooth Mousse, a complex containing amorphous calcium phosphate (ACP) and casein phosphopeptide (CPP), is recommended in dentin hypersensitivity reduction due to its ability to block opened dentinal tubules. It acts synergistically with fluorine in slowing caries progression. Whether CPP-ACP can act synergistically with fluorine in the dentin hypersensitivity treatment is unknown. The aim of this study was to assess the effect of CPP-ACP combined with fluoride varnish in cervical dentin hypersensitivity treatment.

Dentin Hypersensitivity

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Retrospective
Official Title: Combined Tooth Mousse and Fluoride Varnish in Dentin Hypersensitivity Treatment

Resource links provided by NLM:

Further study details as provided by Huazhong University of Science and Technology:

Primary Outcome Measures:
  • ANOVA [ Time Frame: June 2008 ]

Secondary Outcome Measures:
  • T-test [ Time Frame: June 2008 ]

Enrollment: 30
Study Start Date: January 2007
Study Completion Date: June 2008
Primary Completion Date: January 2008 (Final data collection date for primary outcome measure)
Tooth Mousse
fluoride varnish
Tooth Mousse + fluoride varnish


Ages Eligible for Study:   26 Years to 66 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
primary care clinic

Inclusion Criteria:

  • subjects with a minimum of three cervical hypersensitive teeth at both sides of the dental arch

Exclusion Criteria:

  • dentin hypersensitivity caused by caries lesions
  • fracture of restoration
  • chipped teeth
  • marginal gaps
  • post-operative sensitivity
  • cracked-tooth syndrome, and which were confirmed by periapical radiographs and teeth with cervical fillings
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00926484

China, Hubei
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China, 430030
Sponsors and Collaborators
Huazhong University of Science and Technology
National Natural Science Foundation of China
Study Chair: Xuejin Tao, Doctor Tongji Hospital
  More Information

Additional Information:
Responsible Party: Weimin Chen, Tongji Hospital, Huazhong University of Science and Technology Identifier: NCT00926484     History of Changes
Other Study ID Numbers: TF87330244
Study First Received: June 22, 2009
Last Updated: June 22, 2009

Keywords provided by Huazhong University of Science and Technology:
Dentin hypersensitivity
Tooth Mousse
fluoride varnish

Additional relevant MeSH terms:
Dentin Sensitivity
Immune System Diseases
Tooth Diseases
Stomatognathic Diseases
Fluorides, Topical
Cariostatic Agents
Protective Agents
Physiological Effects of Drugs processed this record on April 26, 2017