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Tooth Mousse and Fluoride in Dentin Hypersensitivity Treatment

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ClinicalTrials.gov Identifier: NCT00926484
Recruitment Status : Completed
First Posted : June 23, 2009
Last Update Posted : June 23, 2009
Sponsor:
Collaborator:
National Natural Science Foundation of China
Information provided by:
Huazhong University of Science and Technology

Brief Summary:
GC Tooth Mousse, a complex containing amorphous calcium phosphate (ACP) and casein phosphopeptide (CPP), is recommended in dentin hypersensitivity reduction due to its ability to block opened dentinal tubules. It acts synergistically with fluorine in slowing caries progression. Whether CPP-ACP can act synergistically with fluorine in the dentin hypersensitivity treatment is unknown. The aim of this study was to assess the effect of CPP-ACP combined with fluoride varnish in cervical dentin hypersensitivity treatment.

Condition or disease
Dentin Hypersensitivity

Study Type : Observational
Actual Enrollment : 30 participants
Observational Model: Case-Only
Time Perspective: Retrospective
Official Title: Combined Tooth Mousse and Fluoride Varnish in Dentin Hypersensitivity Treatment
Study Start Date : January 2007
Actual Primary Completion Date : January 2008
Actual Study Completion Date : June 2008

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Allergy
U.S. FDA Resources

Group/Cohort
Tooth Mousse
fluoride varnish
Tooth Mousse + fluoride varnish



Primary Outcome Measures :
  1. ANOVA [ Time Frame: June 2008 ]

Secondary Outcome Measures :
  1. T-test [ Time Frame: June 2008 ]


Information from the National Library of Medicine

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Ages Eligible for Study:   26 Years to 66 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
primary care clinic
Criteria

Inclusion Criteria:

  • subjects with a minimum of three cervical hypersensitive teeth at both sides of the dental arch

Exclusion Criteria:

  • dentin hypersensitivity caused by caries lesions
  • fracture of restoration
  • chipped teeth
  • marginal gaps
  • post-operative sensitivity
  • cracked-tooth syndrome, and which were confirmed by periapical radiographs and teeth with cervical fillings

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00926484


Locations
China, Hubei
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China, 430030
Sponsors and Collaborators
Huazhong University of Science and Technology
National Natural Science Foundation of China
Investigators
Study Chair: Xuejin Tao, Doctor Tongji Hospital

Additional Information:
Publications:
Responsible Party: Weimin Chen, Tongji Hospital, Huazhong University of Science and Technology
ClinicalTrials.gov Identifier: NCT00926484     History of Changes
Other Study ID Numbers: TF87330244
First Posted: June 23, 2009    Key Record Dates
Last Update Posted: June 23, 2009
Last Verified: June 2009

Keywords provided by Huazhong University of Science and Technology:
Dentin hypersensitivity
Tooth Mousse
fluoride varnish

Additional relevant MeSH terms:
Hypersensitivity
Dentin Sensitivity
Immune System Diseases
Tooth Diseases
Stomatognathic Diseases
Fluorides
Fluorides, Topical
Cariostatic Agents
Protective Agents
Physiological Effects of Drugs