The Early Origins of Cardiovascular Disease
|ClinicalTrials.gov Identifier: NCT00923039|
Recruitment Status : Unknown
Verified June 2009 by Danone Institute International.
Recruitment status was: Not yet recruiting
First Posted : June 18, 2009
Last Update Posted : June 18, 2009
Small body size at birth, slow weight gain during infancy and increase in body mass index after 2 years are independent risk factors for cardiovascular disease and the metabolic syndrome. There is a large gap in our understanding of how early growth affects the cardiovascular system. Possible mechanisms include alterations in body composition, in cardiac structure, in vascular function, in renal function and epigenetic processes.
The Objective is to determine how size at birth and growth during infancy and childhood affect: body composition, cardiac structure and function, vascular and endothelial function, renal function, metabolic status and transcriptional and epigenetic characteristics.
|Condition or disease|
|Study Type :||Observational|
|Estimated Enrollment :||200 participants|
|Official Title:||The Early Origins of Cardiovascular Disease : the Consequence of Growth Restriction During Foetal Life and Infancy on Cardiovascular Structure and Function in Adulthood|
|Study Start Date :||June 2009|
|Exposed/ Not exposed|
- To determine how size at birth and growth during infancy and childhood affect: body composition, cardiac structure and function, vascular and endothelial function, renal function, metabolic status and transcriptional and epigenetic characteristics [ Time Frame: 3 years ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00923039
|Contact: Umberto SIMEONI, MD,PhD||33 (0)4 91 38 40 email@example.com|
|Contact: Olivier BLIN, MD,PhD||33 (0)4 91 38 75 firstname.lastname@example.org|
|CIC-UPCET Hopital de la Timone Bat F||Not yet recruiting|
|Marseille, France, 13385|
|Contact: Olivier BLIN, MD +33 (0) 491 387 563 email@example.com|