Is it Possible to Screen for Type 2 Diabetes at Day 2 in Gestational Diabetes Mellitus Patients Postpartum? (DG4)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00921882
Recruitment Status : Completed
First Posted : June 16, 2009
Last Update Posted : May 3, 2018
Information provided by (Responsible Party):
Jean-Luc Ardilouze, Université de Sherbrooke

Brief Summary:
Within 6 months of delivery, women who had gestational diabetes mellitus should be screened for type 2 diabetes with a fasting plasma glucose test and/or a 2-h postchallenge glycemia in a 75-g oral glucose tolerance test. However, not all women are screened. The objective of this study is to compare the screening test for type 2 diabetes done at 48 hours post-partum versus 8 weeks post-partum. The investigators want to measure the specificity, sensitivity, false and true predictive values of the screening test at 48 hours post-partum compared to the gold-standard.

Condition or disease Intervention/treatment
Gestational Diabetes Mellitus Type 2 Diabetes Procedure: Oral glucose tolerance test

Study Type : Observational
Actual Enrollment : 51 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Is it Possible to Screen for Type 2 Diabetes at Day 2 Gestational Diabetes Mellitus Postpartum?
Actual Study Start Date : June 2008
Actual Primary Completion Date : October 2012
Actual Study Completion Date : May 2013

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Postpartum Care
Drug Information available for: Dextrose

Group/Cohort Intervention/treatment
Oral glucose tolerance test
oral glucose tolerance test performed 48 hours post-partum and 8 weeks post-partum.
Procedure: Oral glucose tolerance test
Subjects will have the Oral glucose tolerance test 48 hours post-partum and the same test 8 weeks post-partum.

Primary Outcome Measures :
  1. Oral glucose tolerance test [ Time Frame: 8 weeks post partum ]
    Sensitivity, specificity, true and false predictive values of the oral glucose tolerance test

Secondary Outcome Measures :
  1. Acceptability of screening test [ Time Frame: 8 weeks post partum ]
    Prefered moment to do the screening test (48 hours post partum or 8 weeks post partum)

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 45 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Women with gestational diabetes mellitus who delivered.

Inclusion Criteria:

  • Dx of gestational diabetes treated with insulin
  • To be in post-partum
  • Delivery of a baby of at least 37 weeks of gestation
  • Have signed the consent form

Exclusion Criteria:

  • History of glucose intolerance of diabetes before the pregnancy
  • Obstetrical pathology during pregnancy

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00921882

Canada, Quebec
Centre hospitalier universitaire de Sherbrooke
Sherbrooke, Quebec, Canada, J1H 5N4
Sponsors and Collaborators
Université de Sherbrooke
Principal Investigator: Jean-Luc Ardilouze, MD, PhD Université de Sherbrooke

Responsible Party: Jean-Luc Ardilouze, Endocrinologist, researcher, Université de Sherbrooke Identifier: NCT00921882     History of Changes
Other Study ID Numbers: 07-084
First Posted: June 16, 2009    Key Record Dates
Last Update Posted: May 3, 2018
Last Verified: May 2018

Keywords provided by Jean-Luc Ardilouze, Université de Sherbrooke:
Type 2 diabetes
Post-partum screening

Additional relevant MeSH terms:
Diabetes Mellitus
Diabetes Mellitus, Type 2
Diabetes, Gestational
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases
Pregnancy Complications