Ultrastructural Changes of Trabeculectomy Specimens in Patients With Uveitic Secondary Glaucoma

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00917670
Recruitment Status : Completed
First Posted : June 10, 2009
Last Update Posted : July 22, 2010
University of Erlangen-Nürnberg Medical School
Information provided by:
St. Franziskus Hospital

Brief Summary:

Ultrastructural analysis of trabeculectomy specimens of patients with uveitic secondary glaucoma.

To evaluate morphological changes and to compare to primary open angle glaucoma patients.

Condition or disease
Uveitis Secondary Glaucoma

Study Type : Observational
Estimated Enrollment : 10 participants
Observational Model: Case-Only
Time Perspective: Prospective
Study Start Date : May 2009
Actual Primary Completion Date : September 2009
Actual Study Completion Date : December 2009

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Glaucoma

Primary Outcome Measures :
  1. morphological changes [ Time Frame: after surgery ]

Biospecimen Retention:   Samples With DNA
trabeculectomy specimens including trabecular meshwork and Schlemms canal

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with uveitic secondary glaucoma in need of surgical intervention.

Inclusion Criteria:

  • secondary uveitic glaucoma
  • IOP > 24 mmhg with topical and/or systemic therapy
  • need for surgical intervention to control IOP

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00917670

Department of Anatomy II at University of Erlangen, Germany
Erlangen, Germany
Sponsors and Collaborators
St. Franziskus Hospital
University of Erlangen-Nürnberg Medical School

Additional Information:
Responsible Party: Department of Ophthalmology at St. Franziskus Hospital Identifier: NCT00917670     History of Changes
Other Study ID Numbers: 2009-200-f-S-
First Posted: June 10, 2009    Key Record Dates
Last Update Posted: July 22, 2010
Last Verified: July 2010

Keywords provided by St. Franziskus Hospital:
trabecular meshwork
electron microscopy

Additional relevant MeSH terms:
Neoplasm Metastasis
Neoplastic Processes
Pathologic Processes
Ocular Hypertension
Eye Diseases
Uveal Diseases