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Ultrastructural Changes of Trabeculectomy Specimens in Patients With Uveitic Secondary Glaucoma

This study has been completed.
University of Erlangen-Nürnberg Medical School
Information provided by:
St. Franziskus Hospital Identifier:
First received: June 9, 2009
Last updated: July 21, 2010
Last verified: July 2010

Ultrastructural analysis of trabeculectomy specimens of patients with uveitic secondary glaucoma.

To evaluate morphological changes and to compare to primary open angle glaucoma patients.

Uveitis Secondary Glaucoma

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by St. Franziskus Hospital:

Primary Outcome Measures:
  • morphological changes [ Time Frame: after surgery ]

Biospecimen Retention:   Samples With DNA
trabeculectomy specimens including trabecular meshwork and Schlemms canal

Estimated Enrollment: 10
Study Start Date: May 2009
Study Completion Date: December 2009
Primary Completion Date: September 2009 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with uveitic secondary glaucoma in need of surgical intervention.

Inclusion Criteria:

  • secondary uveitic glaucoma
  • IOP > 24 mmhg with topical and/or systemic therapy
  • need for surgical intervention to control IOP
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Please refer to this study by its identifier: NCT00917670

Department of Anatomy II at University of Erlangen, Germany
Erlangen, Germany
Sponsors and Collaborators
St. Franziskus Hospital
University of Erlangen-Nürnberg Medical School
  More Information

Additional Information:
Responsible Party: Department of Ophthalmology at St. Franziskus Hospital Identifier: NCT00917670     History of Changes
Other Study ID Numbers: 2009-200-f-S-
Study First Received: June 9, 2009
Last Updated: July 21, 2010

Keywords provided by St. Franziskus Hospital:
trabecular meshwork
electron microscopy

Additional relevant MeSH terms:
Neoplasm Metastasis
Neoplastic Processes
Pathologic Processes
Ocular Hypertension
Eye Diseases
Uveal Diseases processed this record on June 23, 2017