Ultrastructural Changes of Trabeculectomy Specimens in Patients With Uveitic Secondary Glaucoma

This study has been completed.
University of Erlangen-Nürnberg Medical School
Information provided by:
St. Franziskus Hospital
ClinicalTrials.gov Identifier:
First received: June 9, 2009
Last updated: July 21, 2010
Last verified: July 2010

Ultrastructural analysis of trabeculectomy specimens of patients with uveitic secondary glaucoma.

To evaluate morphological changes and to compare to primary open angle glaucoma patients.

Secondary Glaucoma

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by St. Franziskus Hospital:

Primary Outcome Measures:
  • morphological changes [ Time Frame: after surgery ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA
trabeculectomy specimens including trabecular meshwork and Schlemms canal

Estimated Enrollment: 10
Study Start Date: May 2009
Study Completion Date: December 2009
Primary Completion Date: September 2009 (Final data collection date for primary outcome measure)

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with uveitic secondary glaucoma in need of surgical intervention.

Inclusion Criteria:

  • secondary uveitic glaucoma
  • IOP > 24 mmhg with topical and/or systemic therapy
  • need for surgical intervention to control IOP
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00917670

Department of Anatomy II at University of Erlangen, Germany
Erlangen, Germany
Sponsors and Collaborators
St. Franziskus Hospital
University of Erlangen-Nürnberg Medical School
  More Information

Additional Information:
No publications provided

Responsible Party: Department of Ophthalmology at St. Franziskus Hospital
ClinicalTrials.gov Identifier: NCT00917670     History of Changes
Other Study ID Numbers: 2009-200-f-S- 
Study First Received: June 9, 2009
Last Updated: July 21, 2010
Health Authority: Germany: Ministry of Health

Keywords provided by St. Franziskus Hospital:
trabecular meshwork
electron microscopy

Additional relevant MeSH terms:
Neoplasm Metastasis
Eye Diseases
Neoplastic Processes
Ocular Hypertension
Pathologic Processes

ClinicalTrials.gov processed this record on February 04, 2016