Try our beta test site
IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more...

Structure and Function of Salivary Proteins

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified June 2009 by Boston Children’s Hospital.
Recruitment status was:  Recruiting
Tufts University
Boston University
Boston Medical Center
University of North Carolina, Chapel Hill
Ahura Scientific, Inc.
Information provided by:
Boston Children’s Hospital Identifier:
First received: June 5, 2009
Last updated: June 8, 2009
Last verified: June 2009
This study seeks to provide point-of-care clinical diagnostic systems for the diagnosis of current disease status using saliva as a sample specimen.

Cystic Fibrosis

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Structure and Function of Salivary Proteins

Resource links provided by NLM:

Further study details as provided by Boston Children’s Hospital:

Estimated Enrollment: 200
Study Start Date: November 2007
Estimated Primary Completion Date: February 2010 (Final data collection date for primary outcome measure)
Cystic Fibrosis

Detailed Description:
The overall hypothesis of this study is that whole saliva and its components, due to its direct anatomic relation to the airways, provides a window on the composition and nature of the disease-specific response in the bronchial, sinus, and nasal airways. By examining proteins created in saliva, we hope to validate that saliva is an important diagnostic tool for for rapid analysis of respiratory status. We further propose that rapid salivary diagnostics will improve patient care in prevalent respiratory diseases with frequent health care utilization and high morbidity, such as asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis (CF).

Ages Eligible for Study:   6 Years and older   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Subjects will be approached during their pulmonary clinic appointment or while they are inpatient at Children's Hospital, Boston.

Inclusion Criteria:

  • 6 or more years of age
  • confirmed Cystic Fibrosis

Exclusion Criteria:

  • Pregnant
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00916682

Contact: Lamia Momen 617-355-6665

United States, Massachusetts
Children's Hosptital, Boston Recruiting
Boston, Massachusetts, United States, 02115
Contact: Lamia Momen    617-355-6665   
Principal Investigator: Ahmet Uluer, DO         
Sponsors and Collaborators
Boston Children’s Hospital
Tufts University
Boston University
Boston Medical Center
University of North Carolina, Chapel Hill
Ahura Scientific, Inc.
Principal Investigator: Ahmet Uluer, DO Boston Children’s Hospital
  More Information

Additional Information:
Responsible Party: Ahmet Uluer, DO, Children's Hospital, Boston Identifier: NCT00916682     History of Changes
Other Study ID Numbers: X07-03-0142
Study First Received: June 5, 2009
Last Updated: June 8, 2009

Additional relevant MeSH terms:
Cystic Fibrosis
Pancreatic Diseases
Digestive System Diseases
Lung Diseases
Respiratory Tract Diseases
Genetic Diseases, Inborn
Infant, Newborn, Diseases processed this record on April 26, 2017