Prevention of Potentially Inappropriate Prescribing in Late Life Using Screening Tool of Older Persons' Potentially Inappropriate Prescriptions (STOPP) and Screening Tool to Alert Doctors to Right Treatment (START) Criteria
The recruitment status of this study is unknown because the information has not been verified recently.
Verified October 2009 by Cork University Hospital.
Recruitment status was Active, not recruiting
Recruitment status was Active, not recruiting
Sponsor:
Cork University Hospital
Information provided by:
Cork University Hospital
ClinicalTrials.gov Identifier:
NCT00915824
First received: June 4, 2009
Last updated: October 28, 2009
Last verified: October 2009
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Purpose
Potentially inappropriate prescribing is common in older patients and encompasses overuse, misuse and underuse of medications. Potentially inappropriate prescribing is associated with negative outcomes including adverse drug events and hospitalization.
STOPP (Screening Tool of Older Person's potentially inappropriate Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment) is a new screening tool designed to detect instances of potentially inappropriate medication use and under-prescribing of clinically indicated medications in older patients. The purpose of this study is to determine whether clinical implementation of STOPP/START criteria in hospitalized older patients is effective in improving prescribing quality.
| Condition | Intervention | Phase |
|---|---|---|
|
Healthy |
Other: STOPP/START criteria |
Phase 4 |
| Study Type: | Interventional |
| Study Design: | Allocation: Randomized Endpoint Classification: Safety/Efficacy Study Intervention Model: Parallel Assignment Masking: Open Label |
| Official Title: | Prevention of Potentially Inappropriate Prescribing in Late Life Using STOPP (Screening Tool of Older Persons' Potentially Inappropriate Prescriptions) and START (Screening Tool to Alert Doctors to Right i.e. Appropriate Indicated Treatment): A Randomized Controlled Trial. |
Further study details as provided by Cork University Hospital:
Primary Outcome Measures:
- Appropriateness of prescribing using the Medication Appropriateness Index and the Assessment of Underutilization of Medication Tool [ Time Frame: Measured on admission, discharge and at 2, 4 and 6 months post-discharge ] [ Designated as safety issue: Yes ]
Secondary Outcome Measures:
- Composite health resource utilization including hospital readmission and primary care consultations [ Time Frame: at 2, 4 and 6 months post-discharge ] [ Designated as safety issue: No ]
| Enrollment: | 400 |
| Study Start Date: | November 2007 |
| Estimated Study Completion Date: | June 2009 |
| Primary Completion Date: | June 2009 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
|
Experimental: STOPP/START intervention
STOPP/START intervention group
|
Other: STOPP/START criteria
Application of STOPP/START criteria to the patient's prescription and diagnostic information with subsequent written recommendation on pharmaceutical care to the patient's medical team
|
Eligibility| Ages Eligible for Study: | 65 Years and older (Adult, Senior) |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
Criteria
Inclusion Criteria:
- All patients aged 65 years and older admitted to the general medical services of Cork University Hospital, Cork, Ireland
Exclusion Criteria:
- Patient admitted to a geriatric medicine service, psychiatry of old age service or clinical pharmacology service, or under review of these services during the previous 12 months
- Critically ill patient (admitted to the intensive care unit)
- Terminally ill patient
- Refusal of patient or hospital physician to participate
- No time for the research physician to enrol the patient within 3 days of admission
Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00915824
Please refer to this study by its ClinicalTrials.gov identifier: NCT00915824
Locations
| Ireland | |
| Cork University Hospital | |
| Cork, Ireland | |
Sponsors and Collaborators
Cork University Hospital
Investigators
| Principal Investigator: | Paul Gallagher, MB MRCPI | Cork University Hospital |
| Study Director: | Denis O'Mahony, MD FRCPI | Cork University Hospital |
More Information
| Responsible Party: | Dr. Paul Gallagher, Clinical Research Fellow, Department of Geriatric Medicine, Cork University Hospital |
| ClinicalTrials.gov Identifier: | NCT00915824 History of Changes |
| Other Study ID Numbers: | CRT2006029 |
| Study First Received: | June 4, 2009 |
| Last Updated: | October 28, 2009 |
| Health Authority: | Ireland: Ministry of Health |
Keywords provided by Cork University Hospital:
|
Drug therapy Prescribing Appropriateness Randomized controlled trial |
STOPP/START criteria Appropriateness of prescribing in older patients Prescription Drugs |
ClinicalTrials.gov processed this record on September 28, 2016