Prevention of Potentially Inappropriate Prescribing in Late Life Using Screening Tool of Older Persons' Potentially Inappropriate Prescriptions (STOPP) and Screening Tool to Alert Doctors to Right Treatment (START) Criteria

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.

Verified October 2009 by Cork University Hospital.
Recruitment status was: Active, not recruiting

Sponsor:

Information provided by:

Cork University Hospital

ClinicalTrials.gov Identifier:

NCT00915824

First received: June 4, 2009

Last updated: October 28, 2009

Last verified: October 2009

History of Changes

Purpose

Potentially inappropriate prescribing is common in older patients and encompasses overuse, misuse and underuse of medications. Potentially inappropriate prescribing is associated with negative outcomes including adverse drug events and hospitalization.

STOPP (Screening Tool of Older Person's potentially inappropriate Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment) is a new screening tool designed to detect instances of potentially inappropriate medication use and under-prescribing of clinically indicated medications in older patients. The purpose of this study is to determine whether clinical implementation of STOPP/START criteria in hospitalized older patients is effective in improving prescribing quality.

Condition	Intervention	Phase
Healthy	Other: STOPP/START criteria	Phase 4


Study Type:	Interventional
Study Design:	Allocation: Randomized Intervention Model: Parallel Assignment Masking: Open Label
Official Title:	Prevention of Potentially Inappropriate Prescribing in Late Life Using STOPP (Screening Tool of Older Persons' Potentially Inappropriate Prescriptions) and START (Screening Tool to Alert Doctors to Right i.e. Appropriate Indicated Treatment): A Randomized Controlled Trial.

Further study details as provided by Cork University Hospital:

Primary Outcome Measures:

Appropriateness of prescribing using the Medication Appropriateness Index and the Assessment of Underutilization of Medication Tool [ Time Frame: Measured on admission, discharge and at 2, 4 and 6 months post-discharge ]

Secondary Outcome Measures:

Composite health resource utilization including hospital readmission and primary care consultations [ Time Frame: at 2, 4 and 6 months post-discharge ]


Enrollment:	400
Study Start Date:	November 2007
Estimated Study Completion Date:	June 2009
Primary Completion Date:	June 2009 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
Experimental: STOPP/START intervention STOPP/START intervention group	Other: STOPP/START criteria Application of STOPP/START criteria to the patient's prescription and diagnostic information with subsequent written recommendation on pharmaceutical care to the patient's medical team

Eligibility


Ages Eligible for Study:	65 Years and older (Adult, Senior)
Sexes Eligible for Study:	All
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

All patients aged 65 years and older admitted to the general medical services of Cork University Hospital, Cork, Ireland

Exclusion Criteria:

Patient admitted to a geriatric medicine service, psychiatry of old age service or clinical pharmacology service, or under review of these services during the previous 12 months
Critically ill patient (admitted to the intensive care unit)
Terminally ill patient
Refusal of patient or hospital physician to participate
No time for the research physician to enrol the patient within 3 days of admission

Contacts and Locations

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Please refer to this study by its ClinicalTrials.gov identifier: NCT00915824

Locations


Ireland
Cork University Hospital
Cork, Ireland

Sponsors and Collaborators

Cork University Hospital

Investigators


Principal Investigator:	Paul Gallagher, MB MRCPI	Cork University Hospital
Study Director:	Denis O'Mahony, MD FRCPI	Cork University Hospital

More Information


Responsible Party:	Dr. Paul Gallagher, Clinical Research Fellow, Department of Geriatric Medicine, Cork University Hospital
ClinicalTrials.gov Identifier:	NCT00915824 History of Changes
Other Study ID Numbers:	CRT2006029
Study First Received:	June 4, 2009
Last Updated:	October 28, 2009

Keywords provided by Cork University Hospital:


Drug therapy Prescribing Appropriateness Randomized controlled trial	STOPP/START criteria Appropriateness of prescribing in older patients Prescription Drugs

ClinicalTrials.gov processed this record on June 23, 2017

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