We updated the design of this site on December 18, 2017. Learn more.
ClinicalTrials.gov
ClinicalTrials.gov Menu

Pathways Linking Reduced Sleep Duration and Quality to Obesity Risk

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00915707
Recruitment Status : Completed
First Posted : June 8, 2009
Last Update Posted : September 5, 2013
Sponsor:
Information provided by (Responsible Party):
University of Chicago

Brief Summary:
This study is designed to study the pathways through which short sleep duration or poor sleep quality can lead to an increased risk of developing diabetes and obesity.

Condition or disease Intervention/treatment
Obesity Diabetes Other: Baseline Other: Sleep restriction Other: Reduced Sleep Quality

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 23 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single (Participant)
Official Title: Pathways Linking Reduced Sleep Duration and Quality to Obesity Risk
Study Start Date : January 2007
Primary Completion Date : July 2012
Study Completion Date : July 2012

Arm Intervention/treatment
Experimental: Baseline
Subjects are tested under normal sleep conditions for carbohydrate metabolism and appetite regulation.
Other: Baseline
Subjects are allowed time in bed for sleep as their usual time at home.
Experimental: Sleep restriction
Subjects are tested under sleep restriction for carbohydrate metabolism and appetite regulation.
Other: Sleep restriction
Subjects sleep is reduced to 4.5 hours in bed for 4 nights.
Experimental: Reduced sleep quality
Subjects are tested under a poor sleep quality condition for carbohydrate metabolism and appetite regulation.
Other: Reduced Sleep Quality
Subjects sleep quality is reduced for 4 nights.



Primary Outcome Measures :
  1. Disposition Index reflecting Diabetes Risk as a result of decreased sleep duration and/or quality. [ Time Frame: 3 months ]


Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 30 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Normal weight
  • Healthy
  • Normal sleep times

Exclusion Criteria:

  • Sleep disorders
  • Overweight
  • Diabetes
  • Other health conditions
  • Excessive caffeine and alcohol intake
  • Smoking

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00915707


Locations
United States, Illinois
The University of Chicago
Chicago, Illinois, United States, 60637
Sponsors and Collaborators
University of Chicago
Investigators
Principal Investigator: Esra Tasali, MD University of Chicago

Responsible Party: University of Chicago
ClinicalTrials.gov Identifier: NCT00915707     History of Changes
Other Study ID Numbers: 14916B
First Posted: June 8, 2009    Key Record Dates
Last Update Posted: September 5, 2013
Last Verified: September 2013

Keywords provided by University of Chicago:
obesity
diabetes, risk
obesity, diabetes risk related to sleep

Additional relevant MeSH terms:
Obesity
Overnutrition
Nutrition Disorders
Overweight
Body Weight
Signs and Symptoms