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Attitudes Towards Buprenorphine and Methadone (Att-1)

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified May 2009 by Psychiatric University Hospital, Zurich.
Recruitment status was:  Recruiting
Information provided by:
Psychiatric University Hospital, Zurich Identifier:
First received: May 28, 2009
Last updated: NA
Last verified: May 2009
History: No changes posted
Main intention of this study is to find out whether there is a difference between the attitudes towards opioid- substitution of opioid dependent patients under substitution with methadone, buprenorphine or without substitution and their therapists

Condition Intervention
Other: interview

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Attitudes of Patients With Opioid-Substitution and Their Therapists Towards and Buprenorphine and Methadone

Resource links provided by NLM:

Further study details as provided by Psychiatric University Hospital, Zurich:

Primary Outcome Measures:
  • Attitude toward buprenorphine compared over the four groups [ Time Frame: one time of measurement ]

Secondary Outcome Measures:
  • Treatment success; Treatment conditions; Consumption of substances [ Time Frame: one point of measurement ]

Estimated Enrollment: 180
Study Start Date: May 2009
Estimated Study Completion Date: June 2010
Estimated Primary Completion Date: September 2009 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
opioid-dependent patients with buprenorphine substitution
Other: interview
interview using questionnaires
Other Name: questionnaire attitudes toward substitution
opioid-dependent patients substituted with methadone
Other: interview
interview using questionnaires
Other Name: questionnaire attitudes toward substitution
no substitution
opioid-dependent patients without substitution
Other: interview
interview using questionnaires
Other Name: questionnaire attitudes toward substitution
therapists of the patients
Other: interview
interview using questionnaires
Other Name: questionnaire attitudes toward substitution

Detailed Description:
Attitudes of patients and therapists can influence therapy success in both directions. Not much is known about patients' and their therapists' attitudes towards substitution medication. Our hypothesis is that the attitude towards buprenorphine is more positive than towards methadone even in patients taking methadone. Better knowledge about the influence of attitudes on treatment success could facilitate to adapt therapy to the patients' needs.

Ages Eligible for Study:   18 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Patients of therapeutic communities, in- and out-patients and their therapists

Inclusion Criteria:

  • Age between 18 and 65 years
  • Opioid-dependent with substitution with buprenorphine,
  • methadone or without substitution
  • Sufficient knowledge of German language

Exclusion Criteria:

  • Inability to give informed consent
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00911846

Psychiatric University Hospital
Zurich, Kanton Zurich, Switzerland, 8032
Sponsors and Collaborators
Psychiatric University Hospital, Zurich
Study Chair: Lukas Boesch, PhD Psychiatric University Hospital, Zurich
  More Information

Responsible Party: Ria Leisinger, Psychiatric University Hospital Zurich Identifier: NCT00911846     History of Changes
Other Study ID Numbers: E-10/2009 
Study First Received: May 28, 2009
Last Updated: May 28, 2009

Keywords provided by Psychiatric University Hospital, Zurich:
opioid dependence substitution buprenorphine methadone

Additional relevant MeSH terms:
Analgesics, Opioid
Central Nervous System Depressants
Physiological Effects of Drugs
Sensory System Agents
Peripheral Nervous System Agents
Antitussive Agents
Respiratory System Agents
Narcotic Antagonists processed this record on February 17, 2017