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Ventrointermediate Nucleus (VIM DBS) and Working Memory (WMVIM)

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00906412
First Posted: May 21, 2009
Last Update Posted: November 10, 2016
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Washington University School of Medicine
  Purpose
This is part of a larger study for which participants have already completed memory and thinking tests. In this study, investigators are trying to learn how deep-brain stimulation affects memory skills in essential tremor (ET) patients. We are especially trying to figure out how stimulation on each side of the brain may affect working memory.

Condition
Essential Tremor

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: VIM DBS and Working Memory

Resource links provided by NLM:


Further study details as provided by Washington University School of Medicine:

Enrollment: 10
Study Start Date: September 2006
Study Completion Date: November 2016
Primary Completion Date: September 2013 (Final data collection date for primary outcome measure)
Groups/Cohorts
ET Group
Total of 25 participants with ET
Controls
25 controls without ET

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   40 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Washington University School of Medicine Movement Disorder Clinic
Criteria

Inclusion Criteria:

ET PATIENTS:

  • Clinical diagnosis of essential tremor affecting the upper extremities.
  • Previous unilateral or bilateral DBS of the VIM
  • Ages 40 -70
  • A useable pre-surgical MR scan

CONTROLS:

  • Spouse or acquaintance of enrolled patient participant
  • Ages 40 - 70

Exclusion Criteria:

ET PATIENTS:

  • Clinical evidence of other neurological conditions
  • Significant psychiatric condition

CONTROLS:

  • Clinical evidence of other neurological conditions
  • Significant psychiatric condition
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00906412


Locations
United States, Missouri
Washington University School of Medicine
St. Louis, Missouri, United States, 63110
Sponsors and Collaborators
Washington University School of Medicine
Investigators
Principal Investigator: Hershey Tamara, PhD Washington University School of Medicine
  More Information

Responsible Party: Washington University School of Medicine
ClinicalTrials.gov Identifier: NCT00906412     History of Changes
Other Study ID Numbers: 06-0732
First Submitted: May 19, 2009
First Posted: May 21, 2009
Last Update Posted: November 10, 2016
Last Verified: November 2016
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No
Plan Description: This is a small pilot study and consent to share data was not obtained.

Keywords provided by Washington University School of Medicine:
Essential Tremor

Additional relevant MeSH terms:
Tremor
Essential Tremor
Dyskinesias
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms
Movement Disorders
Central Nervous System Diseases