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Ventrointermediate Nucleus (VIM DBS) and Working Memory (WMVIM)

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ClinicalTrials.gov Identifier: NCT00906412
Recruitment Status : Completed
First Posted : May 21, 2009
Last Update Posted : November 10, 2016
Sponsor:
Information provided by (Responsible Party):

Study Description
Brief Summary:
This is part of a larger study for which participants have already completed memory and thinking tests. In this study, investigators are trying to learn how deep-brain stimulation affects memory skills in essential tremor (ET) patients. We are especially trying to figure out how stimulation on each side of the brain may affect working memory.

Condition or disease
Essential Tremor

Study Design

Study Type : Observational
Actual Enrollment : 10 participants
Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: VIM DBS and Working Memory
Study Start Date : September 2006
Primary Completion Date : September 2013
Study Completion Date : November 2016

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Memory Tremor
U.S. FDA Resources

Groups and Cohorts

Group/Cohort
ET Group
Total of 25 participants with ET
Controls
25 controls without ET


Outcome Measures

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   40 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Washington University School of Medicine Movement Disorder Clinic
Criteria

Inclusion Criteria:

ET PATIENTS:

  • Clinical diagnosis of essential tremor affecting the upper extremities.
  • Previous unilateral or bilateral DBS of the VIM
  • Ages 40 -70
  • A useable pre-surgical MR scan

CONTROLS:

  • Spouse or acquaintance of enrolled patient participant
  • Ages 40 - 70

Exclusion Criteria:

ET PATIENTS:

  • Clinical evidence of other neurological conditions
  • Significant psychiatric condition

CONTROLS:

  • Clinical evidence of other neurological conditions
  • Significant psychiatric condition
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00906412


Locations
United States, Missouri
Washington University School of Medicine
St. Louis, Missouri, United States, 63110
Sponsors and Collaborators
Washington University School of Medicine
Investigators
Principal Investigator: Hershey Tamara, PhD Washington University School of Medicine
More Information

Responsible Party: Washington University School of Medicine
ClinicalTrials.gov Identifier: NCT00906412     History of Changes
Other Study ID Numbers: 06-0732
First Posted: May 21, 2009    Key Record Dates
Last Update Posted: November 10, 2016
Last Verified: November 2016
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No
Plan Description: This is a small pilot study and consent to share data was not obtained.

Keywords provided by Washington University School of Medicine:
Essential Tremor

Additional relevant MeSH terms:
Tremor
Essential Tremor
Dyskinesias
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms
Movement Disorders
Central Nervous System Diseases