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Impact of Fibroblast Growth Factor 23 (FGF-23) and Serum Phosphate on Allograft Function and Mortality in Kidney Allograft Recipients

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified December 2009 by Ramathibodi Hospital.
Recruitment status was:  Active, not recruiting
Information provided by:
Ramathibodi Hospital Identifier:
First received: May 1, 2009
Last updated: December 16, 2009
Last verified: December 2009
The present study will examine whether serum FGF-23 and serum phosphate at baseline of kidney transplant recipients can predict progression of allograft dysfunction at 3 years and all-cause mortality at 5 years.

Kidney Transplantation

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Impact of FGF-23 and Serum Phosphate on Allograft Function and Mortality in Kidney Allograft Recipients

Resource links provided by NLM:

Further study details as provided by Ramathibodi Hospital:

Primary Outcome Measures:
  • Progression of allograft dysfunction and all-cause Mortality [ Time Frame: 3 and 5 years ]

Secondary Outcome Measures:
  • Relationship of FGF-23 and 25-OH-D, 1-25-OH-D, PTH, calcium, phosphate, urine phosphate and eGFR [ Time Frame: 1 year ]

Biospecimen Retention:   Samples With DNA

Estimated Enrollment: 200
Study Start Date: May 2009
Estimated Study Completion Date: January 2015
Estimated Primary Completion Date: January 2015 (Final data collection date for primary outcome measure)
Kidney transplant recipients


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Kidney transplant recipients

Inclusion Criteria:

  • at least one year post-transplantation
  • no more than 10% increase in serum creatinine for the past 3 months

Exclusion Criteria:

  • refuse to participate in the study
  • any acute illnesses
  Contacts and Locations
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Please refer to this study by its identifier: NCT00903578

Ramathibodi Hospital, Mahidol University
Phayathai, Bangkok, Thailand, 10400
Sponsors and Collaborators
Ramathibodi Hospital
Principal Investigator: Sinee Disthabanchong, M.D. Ramathibodi Hospital, Mahidol University
  More Information

Responsible Party: Sinee Disthabanchong, M.D, Ramathibodi Hospital, Mahidol University Identifier: NCT00903578     History of Changes
Other Study ID Numbers: KT-1
Study First Received: May 1, 2009
Last Updated: December 16, 2009

Keywords provided by Ramathibodi Hospital:
vitamin D
allograft dysfunction
mortality processed this record on May 23, 2017