Quantitative Studies of Urinary Bladder Sensation
The purpose of this study is to determine whether more than one subpopulation exists of patients with the diagnosis of Interstitial Cystitis (IC) based on sensory testing and to determine if subjects with IC have normal counterirritation-related modulatory systems.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Quantitative Studies of Urinary Bladder Sensation|
- The study proposes to examine the sensations that are produced by warming the skin, poking the skin, pressure on the muscles or by applying a blood pressure cuff. [ Time Frame: One and a half to two hours ] [ Designated as safety issue: No ]
|Study Start Date:||May 2007|
|Study Completion Date:||November 2009|
|Primary Completion Date:||November 2009 (Final data collection date for primary outcome measure)|
Other: Quantitative Sensory Testing and Stimulus
To determine whether more than one subpopulation exists of patients with the diagnosis of Interstitial Cystitis (IC) based on sensory testing and to determine if subjects with IC have normal counterirritation-related modulatory systems. Previous studies by the PI suggest that two populations of subjects are present in the IC population but a larger number of subjects with IC would need to be tested in order to determine if this were indeed true. Other studies have demonstrated that counterirritation-related effects are absent in several chronic pain populations including fibromyalgia and chronic headaches. Identification of a subset of IC patients or the identification of a failure of counterirritation-related effects may predict responses to therapeutic interventions.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00903435
|United States, Alabama|
|UAB Kirklin Clinic|
|Birmingham, Alabama, United States, 35294|
|Principal Investigator:||Timothy Ness, M.D., Ph.D.||University of Alabama at Birmingham|