Sleep Disordered Breathing and Diabetes

This study has been completed.
Information provided by (Responsible Party):
University of Chicago Identifier:
First received: May 11, 2009
Last updated: September 4, 2013
Last verified: September 2013

The hypothesis of this study is: sleep disordered breathing (SDB), specifically, obstructive sleep apnea, is associated with poorer glucose in the existing type 2 diabetic condition.

In an exploration of this hypothesis, the investigators hope to provide evidence linking SDB to increased severity of disease in the type 2 diabetic patient. By doing so, the investigators ultimately seek to support investigating the use of SDB interventions as an additional method of care in the treatment of type 2 diabetes.

Type 2 Diabetes
Obstructive Sleep Apnea

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Sleep Disordered Breathing and Blood Glucose Control in Type 2 Diabetes

Resource links provided by NLM:

Further study details as provided by University of Chicago:

Primary Outcome Measures:
  • Improvement in glucose tolerance [ Time Frame: Day 1 to day 10. ] [ Designated as safety issue: No ]

Biospecimen Retention:   None Retained
Blood was taken for HbA1C

Enrollment: 105
Study Start Date: February 2007
Study Completion Date: December 2009
Primary Completion Date: November 2008 (Final data collection date for primary outcome measure)
Stable type 2 Diabetes (ST2D)
Adults with Type 2 diabetes who receive medical care at the University of Chicago


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Adult female and male patients with type 2 diabetes who are followed by University of Chicago physicians in the endocrinology or primary care clinic will self-identify themselves for participation in response to flyers posted at the check-in desk.

Inclusion Criteria:

  • adult female and male patients with type 2 diabetes who are followed by University of Chicago physicians

Exclusion Criteria:

  • patients with the diagnosis of type 1 diabetes (DM); newly diagnosed Type 2 DM patients
  • patients with the diagnosis of OSA using CPAP for either 4 or more hours per night or 5 nights per week
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00901472

United States, Illinois
The University of Chicago
Chicago, Illinois, United States, 60637
Sponsors and Collaborators
University of Chicago
Principal Investigator: Eve Van Cauter, PhD University of Chicago
  More Information

No publications provided

Responsible Party: University of Chicago Identifier: NCT00901472     History of Changes
Other Study ID Numbers: #14903B
Study First Received: May 11, 2009
Last Updated: September 4, 2013
Health Authority: United States: Institutional Review Board

Keywords provided by University of Chicago:
Type 2 diabetes,
obstructive sleep apnea

Additional relevant MeSH terms:
Diabetes Mellitus, Type 2
Sleep Apnea, Obstructive
Diabetes Mellitus
Endocrine System Diseases
Glucose Metabolism Disorders
Metabolic Diseases
Nervous System Diseases
Respiration Disorders
Respiratory Tract Diseases
Sleep Apnea Syndromes
Sleep Disorders
Sleep Disorders, Intrinsic processed this record on December 01, 2015