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Time-Dependent Mobilization of Circulating Progenitor Cells During Strenuous Exercise in Healthy Individuals

This study has been completed.
University of Jena
Information provided by (Responsible Party):
Sven Möbius-Winkler, University of Leipzig Identifier:
First received: May 1, 2009
Last updated: October 25, 2016
Last verified: May 2009
Only few data are available on the influence of strenuous exercise on the content of circulating progenitor cells and especially the timeframe of their release. The aim of the present study was to investigate the potential influence of 4 hours of cycling on the time-dependent release of progenitor cells.

Condition Intervention
Healthy Men
Procedure: Exercise

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Basic Science
Official Title: Time Dependent Mobilization of Circulating Progenitor Cells During Strenuous Exercise in Healthy Individuals.

Resource links provided by NLM:

Further study details as provided by University of Leipzig:

Primary Outcome Measures:
  • Endothelial progenitor cells (EPC) release on [ Time Frame: 4 hours ]

Enrollment: 18
Study Start Date: September 2008
Study Completion Date: March 2009
Primary Completion Date: March 2009 (Final data collection date for primary outcome measure)
Detailed Description:
  1. What is the response of hematopoietic and endothelial progenitor cells after a standardized prolonged endurance exercise?
  2. What is the kinetic of cell mobilization during this standardized exercise?

Ages Eligible for Study:   18 Years to 60 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • healthy volunteers

Exclusion Criteria:

  • cardiovascular disease
  Contacts and Locations
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Please refer to this study by its identifier: NCT00900107

University Leipzig, Heart Center
Leipzig, Germany, 04289
Sponsors and Collaborators
University of Leipzig
University of Jena
Study Director: Gerhard C Schuler, Prof. Dr. Heart Center Leipzig
  More Information

Responsible Party: Sven Möbius-Winkler, PD Dr. med., University of Leipzig Identifier: NCT00900107     History of Changes
Other Study ID Numbers: SMW 02
Study First Received: May 1, 2009
Last Updated: October 25, 2016 processed this record on April 28, 2017