Epidermal Growth Factor Receptor Mutations in the Blood of Patients With Advanced Non-Small Cell Lung Cancer
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|ClinicalTrials.gov Identifier: NCT00899756|
Recruitment Status : Unknown
Verified July 2009 by National Cancer Institute (NCI).
Recruitment status was: Recruiting
First Posted : May 12, 2009
Last Update Posted : July 8, 2009
RATIONALE: Collecting and storing samples of blood from patients with cancer to study in the laboratory may help doctors learn more about changes that may occur in DNA and identify biomarkers related to cancer.
PURPOSE: This laboratory study is looking at epidermal growth factor receptor mutations in the blood of patients with advanced non-small cell lung cancer.
|Condition or disease||Intervention/treatment|
|Lung Cancer||Genetic: molecular diagnostic method Genetic: mutation analysis|
- Determine if epidermal growth factor receptor (EGFR) mutation exists in the peripheral blood of patients with advanced non-small cell lung cancer (NSCLC).
- Estimate the frequency of EGFR mutation in these patients.
- Correlate the presence of EGFR mutation in blood with EGFR mutation in primary or metastatic NSCLC tumor block.
OUTLINE: Patients undergo blood collection for analysis of epidermal growth factor receptor mutation by DNA sequencing.
PROJECTED ACCRUAL: A total of 50 patients will be accrued for this study.
|Study Type :||Observational|
|Estimated Enrollment :||50 participants|
|Official Title:||Study of Mutations of Epidermal Growth Factor Receptor in the Blood of Patients With Advanced Non Small Cell Lung Cancer|
|Study Start Date :||June 2006|
- Existence of epidermal growth factor receptor (EGFR) mutations in peripheral blood
- Frequency of EGFR mutation
- Correlation of the presence of EGFR mutation in blood with EFGR mutation in primary or metastatic tumor tissue
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00899756
|Johns Hopkins Singapore International Medical Centre||Recruiting|
|Singapore, Singapore, 308433|
|Contact: Alex Y. Chang, MD 65-6880-2222 firstname.lastname@example.org|
|Study Chair:||Alex Y. Chang, MD||Johns Hopkins Singapore International Medical Centre|