Evaluation of the Effects of Oxygen Therapy and Enalapril for Diabetic Macular Ischemia
|ClinicalTrials.gov Identifier: NCT00899587|
Recruitment Status : Unknown
Verified May 2009 by Shahid Beheshti University of Medical Sciences.
Recruitment status was: Recruiting
First Posted : May 12, 2009
Last Update Posted : May 12, 2009
In this study, patients were divided into 3 group with 35 cases including: 1.oxygen 2.enalapril 3.control.
In the beginning of the study, best corrected visual acuity (BCVA), uncorrected visual acuity (UCVA), and optical coherence tomography (OCT) were measured. Patients in the oxygen group were given oxygen 10 lit/min 1 hour twice a day at the first month, once a day at the second month and every other day at the third month. In the enalapril group, patients were given enalapril 5 mg every night and placebo was given for the patients in third group. At the end of first month the patients' vision was checked again and at the the end of the third month the first physical examinations were performed. In the first group, arterial blood gas (ABG) was taken before and after oxygen therapy as well.
|Condition or disease||Intervention/treatment||Phase|
|Diabetic Macular Ischemia||Drug: enalapril Other: oxygen Drug: placebo||Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Official Title:||Evaluation of the Effects of Oxygen Therapy and Enalapril for Diabetic Macular Ischemia|
oxygen 10 lit/min 1 hour twice a day at the first month, once a day at the second month and every other day at the third month
enalapril 5 mg every night
|Placebo Comparator: Control||Drug: placebo|
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00899587
|Contact: Masoud Soheilian, MDfirstname.lastname@example.org|
|Iran, Islamic Republic of|
|Ophthalmic Research Center||Recruiting|
|Tehran, Iran, Islamic Republic of, 166666|
|Contact: Masoud Soheilian, MD +98 21 22585952 email@example.com|