Tissue Sample Collection From Patients With Fanconi Anemia
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ClinicalTrials.gov Identifier: NCT00899522 |
Recruitment Status
:
Completed
First Posted
: May 12, 2009
Last Update Posted
: December 4, 2017
|
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RATIONALE: Collecting and storing samples of tumor tissue from patients with Fanconi anemia to test in the laboratory may help the study of cancer in the future.
PURPOSE: This laboratory study is collecting and storing tumor tissue samples from patients with Fanconi anemia.
Condition or disease | Intervention/treatment |
---|---|
Fanconi Anemia Unspecified Adult Solid Tumor, Protocol Specific Unspecified Childhood Solid Tumor, Protocol Specific | Other: biologic sample preservation procedure Procedure: biopsy |
OBJECTIVES:
- Acquire rare solid tumor samples from patients with Fanconi anemia in order to create a Fanconi Anemia Cell Repository at the Oregon Health and Science University Cancer Institute.
- Study repository tissue using a variety of molecular methods, including gene microarrays.
- Develop cancer cell lines that are publicly available from tissue archived from patients with Fanconi anemia.
OUTLINE: Tumor biopsies are collected from patients with Fanconi anemia and archived for future molecular studies, cell line generation, and general usage by the research community at large. Medical information about the patient's cancer is also archived.
PROJECTED ACCRUAL: Not specified.
Study Type : | Observational |
Actual Enrollment : | 8 participants |
Observational Model: | Case-Control |
Time Perspective: | Retrospective |
Official Title: | Fanconi Anemia Cancer Cell Repository |
Study Start Date : | August 2005 |
Actual Primary Completion Date : | March 2013 |
Actual Study Completion Date : | May 2013 |

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Other: biologic sample preservation procedure
- Creation of a Fanconi Anemia Cell Repository using rare solid tumor samples from patients with Fanconi anemia [ Time Frame: Duration of the study ]
- Study tissue samples by molecular methods, including gene microarrays [ Time Frame: Duration of the study ]
- Development of cancer cell lines from tissue archived from patients with Fanconi anemia [ Time Frame: Duration of the study ]

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Ages Eligible for Study: | 1 Year to 55 Years (Child, Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Probability Sample |
DISEASE CHARACTERISTICS:
- Confirmed Fanconi anemia
- Confirmed malignant solid tumor
- Biopsy of tumor tissue available
PATIENT CHARACTERISTICS:
- Not specified
PRIOR CONCURRENT THERAPY:
- Not specified

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00899522
United States, Oregon | |
Knight Cancer Institute at Oregon Health and Science University | |
Portland, Oregon, United States, 97239-3098 |
Principal Investigator: | Grover C. Bagby, MD | OHSU Knight Cancer Institute |
Responsible Party: | Grover Bagby, Professor Emeritus, OHSU Knight Cancer Institute |
ClinicalTrials.gov Identifier: | NCT00899522 History of Changes |
Other Study ID Numbers: |
IRB00001100 P30CA069533 ( U.S. NIH Grant/Contract ) OHSU-HEM-03022-LX OHSU-IRB00001100 OSHU-CR00003822 CDR0000445453 ( Other Identifier: NCI PDQ ) |
First Posted: | May 12, 2009 Key Record Dates |
Last Update Posted: | December 4, 2017 |
Last Verified: | November 2017 |
Keywords provided by Grover Bagby, OHSU Knight Cancer Institute:
Fanconi anemia unspecified adult solid tumor, protocol specific unspecified childhood solid tumor, protocol specific |
Additional relevant MeSH terms:
Anemia Fanconi Anemia Anemia, Hypoplastic, Congenital Anemia, Aplastic Neoplasms Fanconi Syndrome Hematologic Diseases Bone Marrow Diseases |
Genetic Diseases, Inborn DNA Repair-Deficiency Disorders Metabolic Diseases Renal Tubular Transport, Inborn Errors Kidney Diseases Urologic Diseases Metabolism, Inborn Errors |