Collecting and Storing Samples of Blood and Tumor Tissue From Patients With Osteosarcoma
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00899275|
Recruitment Status : Active, not recruiting
First Posted : May 12, 2009
Last Update Posted : December 13, 2017
RATIONALE: Collecting and storing samples of tumor tissue and blood from patients to test in the laboratory may help the study of cancer in the future.
PURPOSE: The purpose of this study is to collect and store samples of blood and tumor tissue from patients with osteosarcoma.
|Condition or disease||Intervention/treatment|
|Sarcoma||Other: biologic sample preservation procedure|
- To collect biological specimens from patients with osteosarcoma at Children's Oncology Group (COG) institutions.
- To provide a repository for long-term storage of osteosarcoma-related biological materials.
- To make these specimens available to qualified researchers to understand the biology of osteosarcoma and correlate these results with the patients' clinical data.
OUTLINE: After the initial submission of blood samples, patients may undergo open or closed biopsy in order to obtain fresh and frozen tissue samples as well as paraffin embedded material. Patients who are enrolled at the time of initial diagnosis but then have a definitive surgery or develop recurrent disease may submit additional samples (paraffin block, frozen and fresh tumor tissue, or slides together with blood samples). Autopsy tumor samples may also be submitted.
|Study Type :||Observational|
|Estimated Enrollment :||1000 participants|
|Official Title:||A Children's Oncology Group Protocol for Collecting and Banking Osteosarcoma Specimens|
|Study Start Date :||February 2008|
|Estimated Primary Completion Date :||January 2100|
|Ancillary/Correlative All patients||Other: biologic sample preservation procedure|
- Collect biological specimens from patients with osteosarcoma [ Time Frame: baseline ]
- Provide a repository for long-term storage of osteosarcoma-related biological materials [ Time Frame: length of study ]
- Make these specimens available to qualified researchers to understand the biology of osteosarcoma [ Time Frame: length of study ]
- Correlate these results with the patients' clinical data [ Time Frame: lengh of study ]
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00899275
Show 155 Study Locations
|Study Chair:||Richard Gorlick, MD||Children's Hospital at Montefiore|