Blood Sample Analysis in Predicting Overall Survival in Patients With Recurrent or Metastatic Head and Neck Cancer
|ClinicalTrials.gov Identifier: NCT00898911|
Recruitment Status : Completed
First Posted : May 12, 2009
Last Update Posted : May 17, 2017
RATIONALE: Studying samples of blood in the laboratory from patients with cancer may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how patients will respond to treatment.
PURPOSE: This research study is looking at blood sample analysis in predicting overall survival in patients with recurrent or metastatic head and neck cancer.
|Condition or disease||Intervention/treatment|
|Head and Neck Cancer||Other: matrix-assisted laser desorption/ionization time of flight mass spectrometry|
- To validate the mass spectrometry profile that is predictive of survival benefit in patients with recurrent or metastatic head and neck squamous cell carcinoma treated with EGFR inhibitors.
OUTLINE: Plasma and serum samples are analyzed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and classified according to prognosis ("good" vs "poor") using a previously developed predictive algorithm.
|Study Type :||Observational|
|Actual Enrollment :||30 participants|
|Official Title:||Prediction of Overall Survival Using Mass Spectrometry Profiling in Head and Neck Cancer Patients Treated With Epidermal Growth Factor Receptor Inhibitors|
|Actual Study Start Date :||July 8, 2008|
|Actual Primary Completion Date :||April 8, 2012|
|Actual Study Completion Date :||April 8, 2012|
- Overall survival measured in weeks [ Time Frame: 1 month ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00898911
|Study Chair:||Christine Chung, MD||Vanderbilt-Ingram Cancer Center|