Bone Marrow and Blood Samples From Patients With Metastatic Choroid Melanoma
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|ClinicalTrials.gov Identifier: NCT00897624|
Recruitment Status : Completed
First Posted : May 12, 2009
Last Update Posted : May 13, 2011
RATIONALE: Studying samples of bone marrow and blood from patients with cancer may help doctors find out the extent of disease.
PURPOSE: This research study is collecting bone marrow and blood samples from patients with metastatic choroid melanoma.
|Condition or disease||Intervention/treatment|
|Intraocular Melanoma||Genetic: gene expression analysis Genetic: reverse transcriptase-polymerase chain reaction Other: laboratory biomarker analysis|
- Develop and validate a method of detecting tumor cells in the bone marrow and blood in patients with metastatic choroid melanoma.
OUTLINE: While patients are under general anesthesia for standard treatment of their disease, samples of bone marrow from the iliac crest and blood are collected. Samples are analyzed for the expression of tyrosinase and Melan-a via RT-PCR.
|Study Type :||Observational|
|Estimated Enrollment :||15 participants|
|Official Title:||Evaluation of the Detection of Tumor Cells in Bone Marrow and Blood in Patients With Choroid Melanoma|
|Study Start Date :||November 2007|
|Primary Completion Date :||May 2011|
- Detection of micro-metastatic cells in 20 x 10^6 nucleated cells
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00897624
|Principal Investigator:||Pierre T. Dorval, MD||Institut Curie|