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Interscanner Variation in Musculoskeletal Computed Tomography (CT) Measures (Interscanner)

This study has been completed.
Information provided by:
University of California, San Francisco Identifier:
First received: May 8, 2009
Last updated: June 28, 2010
Last verified: May 2009
Maintaining strong muscles is important for the independence and quality of life in our older population. Strong muscles provide mobility and reduce the chance of falls that lead to injury. Many researchers are carrying out studies to examine different types of exercise and drug treatments to prevent loss of muscle strength in older people. Often, these research studies use x-ray computed tomography (CT) scans to measure the size and the amount of fat in different muscles. These factors are known to reflect muscle health. Large studies can involve many research subjects recruited at many different clinics with different CT scanners. To ensure that these studies provide reliable results, the investigators must have procedures to make sure that different CT scanners measure the same results for the same amount of fat or muscle. The goal of our study is to develop these procedures. In this project, the investigators will study women because they have the highest risk of bone fractures resulting from falls. Thus, the subjects are being asked to volunteer for a study where the subjects will be scanned on different scanners.

Accidental Falls Loss of Muscle Strength

Study Type: Observational
Study Design: Observational Model: Ecologic or Community
Official Title: Inter-scanner Comparison of Muscle Attenuation Measures

Further study details as provided by University of California, San Francisco:

Estimated Enrollment: 20
Study Start Date: May 2009
Study Completion Date: November 2009

Ages Eligible for Study:   60 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
In this project we will study women 60-70 years old because they have the highest risk of bone fractures resulting from falls.

Inclusion Criteria:

  • age 60-70 years old
  • healthy

Exclusion Criteria:

  • no history of spine surgery
  • no history of hip implantation or replacement
  • no scoliosis or other spine deformity
  • not using walking canes or wheelchair
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

No Contacts or Locations Provided
  More Information

Responsible Party: Thomas Lang, PhD Professor in Residence, Department of Radiology, University of California San Francisco Identifier: NCT00896415     History of Changes
Other Study ID Numbers: Inter-scanner study
Study First Received: May 8, 2009
Last Updated: June 28, 2010

Keywords provided by University of California, San Francisco:
on two models of CT scanner acquire CT images of the abdomen pelvis and midthigh in 20 Postmenopausal female volunteers processed this record on September 19, 2017