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Interscanner Variation in Musculoskeletal Computed Tomography (CT) Measures (Interscanner)

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ClinicalTrials.gov Identifier: NCT00896415
Recruitment Status : Completed
First Posted : May 11, 2009
Last Update Posted : June 29, 2010
Sponsor:
Information provided by:
University of California, San Francisco

Brief Summary:
Maintaining strong muscles is important for the independence and quality of life in our older population. Strong muscles provide mobility and reduce the chance of falls that lead to injury. Many researchers are carrying out studies to examine different types of exercise and drug treatments to prevent loss of muscle strength in older people. Often, these research studies use x-ray computed tomography (CT) scans to measure the size and the amount of fat in different muscles. These factors are known to reflect muscle health. Large studies can involve many research subjects recruited at many different clinics with different CT scanners. To ensure that these studies provide reliable results, the investigators must have procedures to make sure that different CT scanners measure the same results for the same amount of fat or muscle. The goal of our study is to develop these procedures. In this project, the investigators will study women because they have the highest risk of bone fractures resulting from falls. Thus, the subjects are being asked to volunteer for a study where the subjects will be scanned on different scanners.

Condition or disease
Accidental Falls Loss of Muscle Strength

Study Type : Observational
Estimated Enrollment : 20 participants
Observational Model: Ecologic or Community
Official Title: Inter-scanner Comparison of Muscle Attenuation Measures
Study Start Date : May 2009
Actual Study Completion Date : November 2009




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Ages Eligible for Study:   60 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
In this project we will study women 60-70 years old because they have the highest risk of bone fractures resulting from falls.
Criteria

Inclusion Criteria:

  • age 60-70 years old
  • healthy

Exclusion Criteria:

  • no history of spine surgery
  • no history of hip implantation or replacement
  • no scoliosis or other spine deformity
  • not using walking canes or wheelchair

Responsible Party: Thomas Lang, PhD Professor in Residence, Department of Radiology, University of California San Francisco
ClinicalTrials.gov Identifier: NCT00896415     History of Changes
Other Study ID Numbers: Inter-scanner study
TLANG_Interscanner
First Posted: May 11, 2009    Key Record Dates
Last Update Posted: June 29, 2010
Last Verified: May 2009

Keywords provided by University of California, San Francisco:
on two models of CT scanner acquire CT images of the abdomen pelvis and midthigh in 20 Postmenopausal female volunteers