Optima Coronary Artery Disease (CAD) (Optimal Mechanical Evaluation)

This study has been completed.
Information provided by (Responsible Party):
University of Pittsburgh
ClinicalTrials.gov Identifier:
First received: May 8, 2009
Last updated: November 21, 2011
Last verified: November 2011
To evaluate the impact of left ventricular (LV) lead location on LV mechanical function.

Heart Failure
Ischemic Cardiomyopathy

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Optima CAD (Optimal Mechanical Evaluation)

Resource links provided by NLM:

Further study details as provided by University of Pittsburgh:

Enrollment: 50
Study Start Date: October 2006

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
18+ years of age must be patients of UPMC Cardiovascular Institute

Inclusion Criteria

  1. Ischemic Cardiomyopathy
  2. Left ventricular ejection fraction less than 40%
  3. Clinical indication for invasive electrophysiology testing
  4. Patient is at least 18 years of age

Exclusion Criteria

  1. Unstable angina, acute myocardial infarction and/or revascularization procedure within 3 months
  2. CVA or TIA within the past 6 months
  3. Prosthetic heart valve
  4. Patient is status post heart transplant
  5. Women who are pregnant or with child -bearing potential and who are not on a reliable form of birth control. Women of child-bearing potential are routinely tested for pregnancy as part of the standard of care prior to EPS procedures being performed.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00896142

United States, Pennsylvania
UPMC Presybterian
Pittsburgh, Pennsylvania, United States, 15213
Sponsors and Collaborators
University of Pittsburgh
Principal Investigator: David S. Schwartzman, MD University of Pittsburgh
  More Information

No publications provided

Responsible Party: University of Pittsburgh
ClinicalTrials.gov Identifier: NCT00896142     History of Changes
Other Study ID Numbers: 0601112 
Study First Received: May 8, 2009
Last Updated: November 21, 2011
Health Authority: United States: Institutional Review Board

Keywords provided by University of Pittsburgh:
ischemic cardiomyopathy
cardiac resynchronization therapy
LV structure and function

Additional relevant MeSH terms:
Cardiovascular Diseases
Heart Diseases

ClinicalTrials.gov processed this record on February 10, 2016