Optima Coronary Artery Disease (CAD) (Optimal Mechanical Evaluation)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00896142
Recruitment Status : Completed
First Posted : May 11, 2009
Last Update Posted : November 22, 2011
Information provided by (Responsible Party):
University of Pittsburgh

Brief Summary:
To evaluate the impact of left ventricular (LV) lead location on LV mechanical function.

Condition or disease
Heart Failure Ischemic Cardiomyopathy

Study Type : Observational
Actual Enrollment : 50 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Optima CAD (Optimal Mechanical Evaluation)
Study Start Date : October 2006

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
18+ years of age must be patients of UPMC Cardiovascular Institute

Inclusion Criteria

  1. Ischemic Cardiomyopathy
  2. Left ventricular ejection fraction less than 40%
  3. Clinical indication for invasive electrophysiology testing
  4. Patient is at least 18 years of age

Exclusion Criteria

  1. Unstable angina, acute myocardial infarction and/or revascularization procedure within 3 months
  2. CVA or TIA within the past 6 months
  3. Prosthetic heart valve
  4. Patient is status post heart transplant
  5. Women who are pregnant or with child -bearing potential and who are not on a reliable form of birth control. Women of child-bearing potential are routinely tested for pregnancy as part of the standard of care prior to EPS procedures being performed.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00896142

United States, Pennsylvania
UPMC Presybterian
Pittsburgh, Pennsylvania, United States, 15213
Sponsors and Collaborators
University of Pittsburgh
Principal Investigator: David S. Schwartzman, MD University of Pittsburgh

Responsible Party: University of Pittsburgh Identifier: NCT00896142     History of Changes
Other Study ID Numbers: 0601112
First Posted: May 11, 2009    Key Record Dates
Last Update Posted: November 22, 2011
Last Verified: November 2011

Keywords provided by University of Pittsburgh:
ischemic cardiomyopathy
cardiac resynchronization therapy
LV structure and function

Additional relevant MeSH terms:
Heart Failure
Heart Diseases
Cardiovascular Diseases