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The In Vitro Fertilization - Lipiodol Uterine Bathing Effect Study

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified May 2009 by University of Auckland, New Zealand.
Recruitment status was:  Recruiting
Information provided by:
University of Auckland, New Zealand Identifier:
First received: May 6, 2009
Last updated: NA
Last verified: May 2009
History: No changes posted
The hypothesis of this study is that Lipiodol uterine bathing improves the success rate of in vitro fertilization (IVF) for women with endometriosis or recurrent IVF implantation failure.

Condition Intervention Phase
In Vitro Fertilization Implantation Failure
Procedure: Lipiodol + IVF
Procedure: IVF
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: The in Vitro Fertilisation - Lipiodol Uterine Bathing Effect Study

Resource links provided by NLM:

Further study details as provided by University of Auckland, New Zealand:

Primary Outcome Measures:
  • Live birth [ Time Frame: 12 months post-randomization ]

Secondary Outcome Measures:
  • Clinical pregnancy [ Time Frame: 3 months post-randomization ]
  • Adverse events [ Time Frame: 3 & 12 months post-randomization ]

Estimated Enrollment: 350
Study Start Date: May 2009
Estimated Study Completion Date: May 2014
Estimated Primary Completion Date: May 2014 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Recurrent IVF implantation failure Procedure: Lipiodol + IVF
IVF preceded by lipiodol
Procedure: IVF
IVF alone
Experimental: Endometriosis Procedure: Lipiodol + IVF
IVF preceded by lipiodol
Procedure: IVF
IVF alone


Ages Eligible for Study:   18 Years to 39 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • 12 or more months infertility
  • Age 18 to 39
  • Endometriosis or recurrent IVF implantation failure
  • Patent fallopian tubes

Exclusion Criteria:

  • Iodine allergy
  • Blocked fallopian tube or tubes
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00894946

Contact: Neil Johnson, MD +64 274360172
Contact: Shelley Reilly, MRANZCOG

New Zealand
University of Auckland Recruiting
Auckland, New Zealand
Contact: Neil Johnson, MD    +64 274 360172   
Principal Investigator: Neil P Johnson, MD         
Sub-Investigator: Shelley J Reilly, MRANZCOG         
Sub-Investigator: Cindy M Farquhar, MD         
Sub-Investigator: Alistair Stewart         
Sponsors and Collaborators
University of Auckland, New Zealand
Principal Investigator: Neil Johnson, MD University of Auckland, New Zealand
  More Information

Responsible Party: Associate Professor Neil Johnson, University of Auckland Identifier: NCT00894946     History of Changes
Other Study ID Numbers: IVF-LUBE
Study First Received: May 6, 2009
Last Updated: May 6, 2009

Keywords provided by University of Auckland, New Zealand:
recurrent IVF implantation failure

Additional relevant MeSH terms:
Genital Diseases, Female
Ethiodized Oil
Antineoplastic Agents processed this record on May 25, 2017