Metabolic Viral Host Properties

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00893308
Recruitment Status : Completed
First Posted : May 6, 2009
Last Update Posted : May 12, 2009
Information provided by:
Hadassah Medical Organization

Brief Summary:
Patients' metabolic properties may affect their immune response. This study aims to assess the effect of hosts' metabolic properties to viral infection.

Condition or disease
HCV Infection

Detailed Description:
Blood samples were drawn from patients with Gaucher disease and healthy individuals, with and without HCV. Blood samples were tested for protein specific T cell proliferation, IFNg and IL-10 using ELISPOT assays, serum IFNg, IL-2, IL-6, IL-10 and IL-4 levels. FACS analysis was used for evaluation of lymphocytes subsets.

Study Type : Observational
Observational Model: Cohort
Time Perspective: Prospective

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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Both male and female volunteers were recruited. with and without HCV infection, with and without Gaucher disease.

Inclusion Criteria:

  • inform consent

Exclusion Criteria:

  • at patients request

Responsible Party: Yaron Ilan, Hadassah medical organization Identifier: NCT00893308     History of Changes
Other Study ID Numbers: 481133- HMO-CTIL
First Posted: May 6, 2009    Key Record Dates
Last Update Posted: May 12, 2009
Last Verified: May 2009