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Association of Bone Quality and Quantity With Vascular Calcification

This study has been withdrawn prior to enrollment.
Information provided by (Responsible Party):
Yebin Jiang, M.D., University of Michigan Identifier:
First received: May 1, 2009
Last updated: June 11, 2014
Last verified: June 2014
The purpose of this study is to determine if there is a link between calcium build up in the veins or arteries (including the veins/arteries of the heart) and deterioration of the bone. This will help understand if there is a connection between heart disease and bone disease.

Condition Intervention
Vascular Calcification
Bone Density
Procedure: CT of the bones

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Diagnostic
Official Title: Association of Bone Quality and Quantity With Vascular Calcification.

Resource links provided by NLM:

Further study details as provided by University of Michigan:

Primary Outcome Measures:
  • To determine if there is a connection between heart disease and bone disease through correlation of bone density with the calcium deposited in the coronary arteries. [ Time Frame: 1 year ]

Enrollment: 0
Study Start Date: February 2009
Study Completion Date: January 2013
Primary Completion Date: January 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Bone Density Scanning
To acquire high resolution images of the bones and aid in determining bone density.
Procedure: CT of the bones
A CT scan will be performed on one arm and one leg for the purpose of acquiring images for this research study.


Ages Eligible for Study:   30 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Male or Female
  • 30 years of age or older
  • Must already be scheduled to have a CT examination of the arteries of the heart

Exclusion Criteria:

  • Diagnosed with bone cancer
  • Previous diagnosis of cancer that's spread to the bone
  • History of cancer that involves bone marrow
  • Any bone disease other than osteoporosis
  • Any disease which leads to serious osteoporosis or vascular calcification such as:

    • kidney disease
    • thyroid and adrenal disease
    • anorexia nervosa
    • secondary osteoporosis
  Contacts and Locations
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Please refer to this study by its identifier: NCT00892853

United States, Michigan
University of Michigan Hospital
Ann Arbor, Michigan, United States, 48109
Sponsors and Collaborators
University of Michigan
Principal Investigator: Yebin Jiang, M.D. University of Michigan Hospital
  More Information

Responsible Party: Yebin Jiang, M.D., Primary Investigator, University of Michigan Identifier: NCT00892853     History of Changes
Other Study ID Numbers: HUM 00022370
Study First Received: May 1, 2009
Last Updated: June 11, 2014

Keywords provided by University of Michigan:

Additional relevant MeSH terms:
Vascular Calcification
Arterial Occlusive Diseases
Vascular Diseases
Cardiovascular Diseases
Calcium Metabolism Disorders
Metabolic Diseases processed this record on April 28, 2017