Exercise Programs in Healthy Young Women at Increased Risk of Developing Breast Cancer
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|ClinicalTrials.gov Identifier: NCT00892515|
Recruitment Status : Unknown
Verified February 2016 by Abramson Cancer Center of the University of Pennsylvania.
Recruitment status was: Active, not recruiting
First Posted : May 4, 2009
Last Update Posted : February 18, 2016
RATIONALE: Exercise may change the risk of developing breast cancer. It is not yet known whether low-intensity exercise or high-intensity exercise is more effective in lowering the risk of breast cancer.
PURPOSE: This randomized clinical trial is studying how well exercise programs work in healthy young women at increased risk of developing breast cancer.
|Condition or disease||Intervention/treatment|
|Breast Cancer Healthy, no Evidence of Disease||Behavioral: exercise intervention Other: counseling intervention Other: gas chromatography Other: immunoenzyme technique Other: immunologic technique Other: laboratory biomarker analysis Other: mass spectrometry Other: physiologic testing Other: questionnaire administration Other: survey administration Procedure: dual x-ray absorptometry Procedure: magnetic resonance imaging Procedure: study of high risk factors|
Show Detailed Description
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||183 participants|
|Official Title:||Women In Steady Exercise Research (WISER) Sister|
|Study Start Date :||October 2008|
|Primary Completion Date :||May 2012|
- Change in the area under the curve for urinary estrogen (E1G-AUC) adjusted for cycle length
- Effects of exercise on variables known to affect or reflect mitogenic activity as related to breast cancer risk
- Changes in other physiologic parameters associated with breast mitotic activity
- Extent to which changes in body composition and body mass mediate observed changes in E1G-AUC
- Relationship between estrogen and progesterone from daily urinary measurements with observed menstrual cycle alterations (i.e., follicular and luteal phase length changes, and ovulatory status)
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00892515
|United States, Pennsylvania|
|Abramson Cancer Center of the University of Pennsylvania|
|Philadelphia, Pennsylvania, United States, 19104-4283|
|Principal Investigator:||Katie Schmitz, PhD||Abramson Cancer Center of the University of Pennsylvania|