Identifying Factors Underlying the Discontinuation of Triptans

This study has been completed.
Merck Sharp & Dohme Corp.
Information provided by (Responsible Party):
Todd J. Schwedt, Mayo Clinic Identifier:
First received: April 27, 2009
Last updated: March 27, 2013
Last verified: March 2013
The objective of this study is to identify reasons migraine patients stop using triptan medications for abortive headache treatment. It is hypothesized that inadequate education of the patient at the time of prescribing the triptan is positively associated with triptan discontinuation.

Medication Adherence

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Identifying Factors Underlying the Discontinuation of Triptans

Further study details as provided by Mayo Clinic:

Enrollment: 292
Study Start Date: August 2009
Study Completion Date: June 2012
Primary Completion Date: June 2012 (Final data collection date for primary outcome measure)
Triptan User
Triptan Discontinued


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Adult Specialty Headache Clinics

Triptan User Inclusion Criteria:

  • Episodic Migraine or Chronic Migraine
  • Have used a triptan medication in the prior 3 months
  • Have used triptan medications for at least 1 year

Triptan Discontinuation Inclusion Criteria:

  • Episodic Migraine or Chronic Migraine
  • Used any triptan medication in the last 2 years
  • Have not used a triptan medication in the last 6 months
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Please refer to this study by its identifier: NCT00890357

United States, Florida
University of South Florida College of Medicine
Tampa, Florida, United States, 33612
United States, Missouri
Washington University School of Medicine
St. Louis, Missouri, United States, 63110
United States, Ohio
Cleveland Clinic Foundation
Cleveland, Ohio, United States, 44195
Sponsors and Collaborators
Mayo Clinic
Merck Sharp & Dohme Corp.
Principal Investigator: Todd Schwedt, MD Mayo Clinic
  More Information

No publications provided by Mayo Clinic

Additional publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Todd J. Schwedt, PI, Mayo Clinic Identifier: NCT00890357     History of Changes
Other Study ID Numbers: 09-0111
Study First Received: April 27, 2009
Last Updated: March 27, 2013
Health Authority: United States: Institutional Review Board processed this record on November 27, 2015