Molecular Markers in Cervical Cancer Screening in the Feasibility of the Mathematical Markov Model Analysis

The recruitment status of this study is unknown because the information has not been verified recently.
Verified April 2009 by Wuhan University.
Recruitment status was  Not yet recruiting
Information provided by:
Wuhan University Identifier:
First received: April 27, 2009
Last updated: NA
Last verified: April 2009
History: No changes posted

The purpose of this study is to:

  1. make p16INK4A as a cervical cancer screening of tumor markers, cytology improve existing diagnostic sensitivity, specificity, repeatability and validity, so as to effectively prompted the early discovery and diagnosis of cervical cancer.
  2. reduce screening costs, screening and benefits into quantitative evaluation, for our country to develop cervical cancer prevention and control strategy to provide a reliable theoretical basis.

Cervical Cancer

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Molecular Markers in Cervical Cancer Screening in the Feasibility of the Mathematical Markov Model Analysis

Resource links provided by NLM:

Further study details as provided by Wuhan University:

Biospecimen Retention:   Samples With DNA
Cervical exfoliated cells

Estimated Enrollment: 200
Study Start Date: April 2009
Estimated Study Completion Date: July 2011
Estimated Primary Completion Date: June 2010 (Final data collection date for primary outcome measure)
Detailed Description:
  1. To carry out large-scale prospective randomized controlled clinical study to evaluate the "cytological molecular markers Detect + P16INK4A" methods of screening accuracy and reliability, as well as the screening method of the biological effects.
  2. Markov set up mathematical model of screening tests to quantify the inputs and the evaluation proceeds. With a view to optimize and perfect a simple, convenient, practical and efficient program of cervical cancer screening.

Ages Eligible for Study:   25 Years to 65 Years
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
residents of a certain town

Inclusion Criteria:

  • Married women aged 25 to 65-year-old with risk factors
  • No tumor and pelvic radiation therapy history
  • Non-pregnant women at present
  Contacts and Locations
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Please refer to this study by its identifier: NCT00889902

Contact: Hong B Cai, Doctor 0086-027-67813044
Contact: Ying J Huang

China, Hubei
People'S Hospital
Wufeng county, Hubei, China
Sponsors and Collaborators
Wuhan University
Study Director: Hong B Cai, Doctor gynecologic oncology department, Zhongnan Hospital of Wuhan University
  More Information

No publications provided

Responsible Party: HB Cai, Wuhan University Identifier: NCT00889902     History of Changes
Other Study ID Numbers: 320.6740
Study First Received: April 27, 2009
Last Updated: April 27, 2009
Health Authority: China: Ethics Committee

Keywords provided by Wuhan University:
Molecular Markers
Cervical Cancer

Additional relevant MeSH terms:
Uterine Cervical Neoplasms
Genital Diseases, Female
Genital Neoplasms, Female
Neoplasms by Site
Urogenital Neoplasms
Uterine Cervical Diseases
Uterine Diseases
Uterine Neoplasms processed this record on November 24, 2015