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Molecular Markers in Cervical Cancer Screening in the Feasibility of the Mathematical Markov Model Analysis

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ClinicalTrials.gov Identifier: NCT00889902
Recruitment Status : Unknown
Verified April 2009 by Wuhan University.
Recruitment status was:  Not yet recruiting
First Posted : April 29, 2009
Last Update Posted : April 29, 2009
Information provided by:
Wuhan University

Brief Summary:

The purpose of this study is to:

  1. make p16INK4A as a cervical cancer screening of tumor markers, cytology improve existing diagnostic sensitivity, specificity, repeatability and validity, so as to effectively prompted the early discovery and diagnosis of cervical cancer.
  2. reduce screening costs, screening and benefits into quantitative evaluation, for our country to develop cervical cancer prevention and control strategy to provide a reliable theoretical basis.

Condition or disease
Cervical Cancer

Detailed Description:
  1. To carry out large-scale prospective randomized controlled clinical study to evaluate the "cytological molecular markers Detect + P16INK4A" methods of screening accuracy and reliability, as well as the screening method of the biological effects.
  2. Markov set up mathematical model of screening tests to quantify the inputs and the evaluation proceeds. With a view to optimize and perfect a simple, convenient, practical and efficient program of cervical cancer screening.

Study Type : Observational
Estimated Enrollment : 200 participants
Observational Model: Case Control
Time Perspective: Prospective
Official Title: Molecular Markers in Cervical Cancer Screening in the Feasibility of the Mathematical Markov Model Analysis
Study Start Date : April 2009
Estimated Primary Completion Date : June 2010
Estimated Study Completion Date : July 2011

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Cervical Cancer
U.S. FDA Resources

Biospecimen Retention:   Samples With DNA
Cervical exfoliated cells

Information from the National Library of Medicine

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Ages Eligible for Study:   25 Years to 65 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
residents of a certain town

Inclusion Criteria:

  • Married women aged 25 to 65-year-old with risk factors
  • No tumor and pelvic radiation therapy history
  • Non-pregnant women at present

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00889902

Contact: Hong B Cai, Doctor 0086-027-67813044 Chb2105@163.com
Contact: Ying J Huang

China, Hubei
People'S Hospital
Wufeng county, Hubei, China
Sponsors and Collaborators
Wuhan University
Study Director: Hong B Cai, Doctor gynecologic oncology department, Zhongnan Hospital of Wuhan University

Responsible Party: HB Cai, Wuhan University
ClinicalTrials.gov Identifier: NCT00889902     History of Changes
Other Study ID Numbers: 320.6740
First Posted: April 29, 2009    Key Record Dates
Last Update Posted: April 29, 2009
Last Verified: April 2009

Keywords provided by Wuhan University:
Molecular Markers
Cervical Cancer

Additional relevant MeSH terms:
Uterine Cervical Neoplasms
Uterine Neoplasms
Genital Neoplasms, Female
Urogenital Neoplasms
Neoplasms by Site
Uterine Cervical Diseases
Uterine Diseases
Genital Diseases, Female