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Effects of Qigong on Type 2 Diabetic Patients

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00885846
Recruitment Status : Completed
First Posted : April 22, 2009
Results First Posted : April 22, 2009
Last Update Posted : November 16, 2015
Seattle Foundation
Information provided by (Responsible Party):
Bastyr University

Brief Summary:

Qigong therapy is a subtle energy-based methodology for preventing and healing diseases that has been practiced with remarkable results in China for about five thousand years. Recently, preliminary studies showed that Qigong exercises improve insulin resistance and glucose metabolism in people with type 2 diabetes. These studies suggest that Qigong therapy might be an effective and valuable complementary modality for treating type 2 diabetes. Type 2 diabetes is a chronic disease marked by abnormally high levels of sugar in the blood. Diabetes is a serious disease, which, if not controlled, can be life threatening.

The purpose of this project is to conduct a randomized, controlled pilot clinical trial to compare the effectiveness of Qigong therapy to mild exercise and conventional treatment in type 2 diabetes and to identify biological and psychological characteristics associated with subjects' responses to Qigong therapy.

Aim 1: To compare the effects on blood sugar and hemoglobin A1c (HbA1c) level between a Qigong therapy group and non-treated control group as well as between Qigong group and a progressive resistance training (PRT) group before, during and after and 12-week intervention.

Hypothesis 1: Both Qigong therapy and PRT will help type 2 diabetic patients reduce blood sugar levels to different degrees through improving insulin resistance. But the levels of reduction of blood sugar will be greater by Qigong therapy than by PRT due to enhanced insulin secretion.

Aim 2: To compare the effects on fasting C-peptide and insulin levels between a Qigong therapy group, a PRT group and a non-treated control group before and after the intervention.

Hypothesis 2: Qigong therapy will increase the endogenous insulin and C-peptide levels by restoring the functions of the pancreas, while PRT will not alter either insulin or C-peptide levels.

Aim 3: To compare the effects of Qigong therapy and PRT on blood cortisol levels and psychological stress levels before, during and after the intervention.

Hypothesis 3: Perceived stress and depression will be improved by Qigong therapy to a greater extent than by PRT, and blood cortisol levels will be reduced to a greater extent with Qigong therapy.

Condition or disease Intervention/treatment Phase
Diabetes Mellitus, Type 2 Other: Qigong therapy Other: Progressive resistance training Not Applicable

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 32 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: A Pilot Study: The Effects of Qigong Therapy on Type 2 Diabetic Patients
Study Start Date : June 2007
Actual Primary Completion Date : January 2008
Actual Study Completion Date : May 2008

Arm Intervention/treatment
Active Comparator: Qigong Therapy Other: Qigong therapy
For 12 weeks, subjects in Qigong therapy group are to follow a disciplined regular practice, 3 times a week for about 30 minutes, including once a week with a certified instructor to lead and check the correctness of their practice.

Active Comparator: PRT Other: Progressive resistance training
For 12 weeks, subjects in the PRT group are to follow a disciplined regular practice, 3 times a week for about 30 minutes, including once a week with a certified instructor to lead and check the correctness of their practice.

No Intervention: Control

Primary Outcome Measures :
  1. Fasting Blood Glucose [ Time Frame: Week 0 (baseline) and week 12 (final) ]

Secondary Outcome Measures :
  1. Fasting C-peptide [ Time Frame: weeks 0 and 12 ]
  2. Fasting Insulin [ Time Frame: weeks 0 and 12 ]
  3. Perceived Stress Scale (PSS) [ Time Frame: weeks 0 and 12 ]
  4. Beck's Depression Inventory (BDI) [ Time Frame: weeks 0 and 12 ]
  5. HOMA-IR Index [ Time Frame: weeks 0 and 12 ]
  6. Fasting Cortisol [ Time Frame: Weeks 0 and 12 ]

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   18 Years to 65 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Diagnosed with type 2 diabetes defined as a glycohemoglobin between 7.5% and 10.5%, and fasting insulin level <40 (IU/ml).
  • Must be controlling their diabetes with diet or may be taking oral medication for at least three months
  • Age 18-65
  • Ability to physically perform Qigong or low-intensity physical exercise
  • Body Mass Index 18-40
  • Have current primary care
  • Willing to monitor blood glucose at least twice a day
  • Willing to maintain a consistent diet during the study, and
  • Sign informed consent

Exclusion Criteria:

  • Significant kidney, liver or heart disease
  • History of drug or alcohol abuse within the past 2 years
  • Current or previous use of insulin
  • Use of dietary supplements that affect blood glucose or insulin
  • Current practice of Qigong (any style)

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00885846

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United States, Washington
Bastyr University Research Center
Kenmore, Washington, United States, 98028-4966
Sponsors and Collaborators
Bastyr University
Seattle Foundation
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Principal Investigator: Guan-Cheng Sun, PhD Bastyr University
Study Director: Jennifer C Lovejoy, PhD Bastyr University
Study Chair: Ryan Bradley, ND Bastyr University

Publications automatically indexed to this study by Identifier (NCT Number):
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Responsible Party: Bastyr University Identifier: NCT00885846    
Other Study ID Numbers: H77B11
First Posted: April 22, 2009    Key Record Dates
Results First Posted: April 22, 2009
Last Update Posted: November 16, 2015
Last Verified: April 2015
Keywords provided by Bastyr University:
Breathing management
Additional relevant MeSH terms:
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Diabetes Mellitus, Type 2
Diabetes Mellitus
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases