We are updating the design of this site. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Prevalence of Renal Artery Stenosis in Patients Referred for Cardiac Catheterization (RAS)

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00885768
First Posted: April 22, 2009
Last Update Posted: May 13, 2011
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
Tehran Heart Center
Information provided by:
Imam Khomeini Hospital
  Purpose
All patients referred for coronary angiography will simultaneously be evaluated for renal artery stenosis and then stenosis more than 50% will be analyzed according to clinical conditions, risk factors and lab data.

Condition Intervention Phase
Renal Artery Stenosis Procedure: angiography Phase 3

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Prevalence of Renal Artery Stenosis in Patients Refered for Cardiac Catheterization to Heart Center Hospital in July-September 2008

Further study details as provided by Imam Khomeini Hospital:

Primary Outcome Measures:
  • Prevalence of Renal Artery Stenosis (RAS) [ Time Frame: 2 months ]
  • The Number of Patients With Renal Artery Stenosis [ Time Frame: 3months ]
    the prevalence of renal artery stenosis in patients with coronary artery disease


Enrollment: 146
Study Start Date: July 2008
Study Completion Date: April 2009
Primary Completion Date: September 2008 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
A
patients with renal artery stenosis
Procedure: angiography
all patients undergoing coronary angiography with VISIPAQUE and if they had coronary stenosis then renal artery angiography will be done. the dose of contrast will be chosen according to renal function and clinical conditions which will be varied from 75 to 300 ml.

Detailed Description:
Renal Artery Stenosis (RAS) is a common finding in patients with generalized atherosclerosis. It is the cause of 15-20% of end stage renal disease in elderly patients. The prevalence of asymptomatic RAS in general population is unknown but it estimated to be 18% in 7th decade and more than 50% in the 8th. It is critical to find and manage the RAS before it's symptoms appear. The Gold standard for diagnosis of atherosclerotic arterial stenosis is angiography. In this study we will evaluate the prevalence, severity, location and related factors to renal artery stenosis in patients whom referred for coronary angiography in period of July-September in one of the most referral heart center in Iran, "The Tehran heart center" which is doing more than 50 coronary angiography daily.
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
All patients reffered to the Tehran Heart center for coronary angiography
Criteria

Inclusion Criteria:

  • age more than 18 years

Exclusion Criteria:

  • contraindication to contrast use
  • not signing consent
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00885768


Locations
Iran, Islamic Republic of
Tehran Heart Center
Tehran, Iran, Islamic Republic of
Sponsors and Collaborators
Imam Khomeini Hospital
Tehran Heart Center
  More Information

Responsible Party: Mohammad Reza Khatami, Kidney Research Center
ClinicalTrials.gov Identifier: NCT00885768     History of Changes
Other Study ID Numbers: RAS001
First Submitted: July 11, 2008
First Posted: April 22, 2009
Results First Submitted: March 9, 2010
Results First Posted: March 23, 2010
Last Update Posted: May 13, 2011
Last Verified: April 2009

Keywords provided by Imam Khomeini Hospital:
RAS(renal Artery Stenosis)
Atherosclerosis
angiography

Additional relevant MeSH terms:
Constriction, Pathologic
Renal Artery Obstruction
Pathological Conditions, Anatomical
Kidney Diseases
Urologic Diseases
Arterial Occlusive Diseases
Vascular Diseases
Cardiovascular Diseases